3-(4-Chlorophenyl)propyl methanesulfonate → HCID 22562298、化合物

HRID 982820

反応式

HRID 982820 の反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]([C:15]([O:17]C)=[O:16])[C:11](=[O:14])[NH:12][N:13]=2)=[CH:4][C:3]=1[CH3:19].CS(O[CH2:25][CH2:26][CH2:27][C:28]1[CH:33]=[CH:32][C:31]([Cl:34])=[CH:30][CH:29]=1)(=O)=O>>[C:15]([C:10]1[C:11](=[O:14])[N:12]([CH2:25][CH2:26][CH2:27][C:28]2[CH:33]=[CH:32][C:31]([Cl:34])=[CH:30][CH:29]=2)[N:13]=[C:8]([C:5]2[CH:6]=[CH:7][C:2]([F:1])=[C:3]([CH3:19])[CH:4]=2)[CH:9]=1)([OH:17])=[O:16]

参加物

3

反応物 2

HCID 130797053-(4-Chlorophenyl)propyl methanesulfonateHCID 219914596-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one

生成物 1

HCID 22562298HCID 22562298、化合物収率 80.8%

実験手順

Following the procedure of Example 1(6), 6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one and 3-(4-chlorophenyl)-1-propanol methanesulfonate were reacted. Without purification, the reaction product was reacted further following the procedure of Example 1(7) to yield the title compound as a yellow crystalline powder (yield: 80.8%).

後処理

  1. customwere reacted
  2. customWithout purification
  3. customthe reaction product was reacted further

出典と根拠

ORDレコード
ord-387871a17f054cf19dc74d2b780ef3cf
出典データセット
uspto-grants-2005_03
特許番号
US06861428B2

関連ノート

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