5-Chloro-2-picolinic acid → N-[3-(2-amino-5,5-difluoro-4-methyl-6H-1,3-oxazin-4-yl)-4-chlorophenyl]-5-chloropyridine-2-carboxamide

反応式

[Cl:19][c:20]1[cH:21][cH:22][c:23]([C:26](=[O:27])[OH:28])[n:24][cH:25]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([Cl:18])[c:6]([C:8]2([CH3:17])[N:9]=[C:10]([NH2:16])[O:11][CH2:12][C:13]2([F:14])[F:15])[cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([Cl:18])[c:6]([C:8]2([CH3:17])[N:9]=[C:10]([NH2:16])[O:11][CH2:12][C:13]2([F:14])[F:15])[cH:7]1)[C:26]([c:23]1[cH:22][cH:21][c:20]([Cl:19])[cH:25][n:24]1)=[O:27]

参加物

反応物 2

HCID 27628725-Chloro-2-picolinic acid

HCID 672338394-(5-amino-2-chlorophenyl)-5,5-difluoro-4-methyl-6H-1,3-oxazin-2-amine

生成物 1

HCID 67233349N-[3-(2-amino-5,5-difluoro-4-methyl-6H-1,3-oxazin-4-yl)-4-chlorophenyl]-5-chloropyridine-2-carboxamide

出典と根拠

ORDレコード: ord-cb217980073a4642a0b241ad943260c0
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…