2,4-Dichlorobenzylidenemalononitrile → 5-(Aminomethyl)-2-(3-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-4-amine

HRID 983859ノート

反応式

HRID 983859 の反応式
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([NH2:7])=[NH:6].[Cl:11][C:12]1[CH:23]=[C:22]([Cl:24])[CH:21]=[CH:20][C:13]=1[CH:14]=[C:15]([C:18]#[N:19])[C:16]#[N:17]>>[NH2:19][CH2:18][C:15]1[C:16]([NH2:17])=[N:6][C:5]([C:4]2[CH:8]=[CH:9][CH:10]=[C:2]([Cl:1])[CH:3]=2)=[N:7][C:14]=1[C:13]1[CH:20]=[CH:21][C:22]([Cl:24])=[CH:23][C:12]=1[Cl:11]

参加物

3

反応物 2

HCID 180892,4-DichlorobenzylidenemalononitrileHCID 2041443-Chloro-benzamidine

生成物 1

HCID 101726815-(Aminomethyl)-2-(3-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidin-4-amine

実験手順

The title compound, MS: m/e=378.8 (M+H+), was prepared from 3-chlorobenzamidine and 2-(2,4-dichloro-benzylidene)-malononitrile in analogy to the process described in Example 11 as a solid.

出典と根拠

ORDレコード
ord-f543be4b77e24d30ad64fff595733f58
出典データセット
uspto-grants-2005_03
特許番号
US06867205B2

反応ノート

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