(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamide → 3-(7-(Triisopropylsilyloxy)methyl-1H-indol-3-yl)-4-(5,6-dihydro-4H-pyrrolo [3,2,1-ij]quinolin-1-yl)-pyrrole-2,5-dione

HRID 983961ノート

反応式

HRID 983961 の反応式
CO[C:3](=[O:27])[C:4]([C:6]1[C:14]2[C:9](=[C:10]([CH2:15][O:16][Si:17]([CH:24]([CH3:26])[CH3:25])([CH:21]([CH3:23])[CH3:22])[CH:18]([CH3:20])[CH3:19])[CH:11]=[CH:12][CH:13]=2)[NH:8][CH:7]=1)=O.[C:28]1([CH2:40][C:41]([NH2:43])=[O:42])[C:38]2=[C:39]3[C:34](=[CH:35][CH:36]=[CH:37]2)[CH2:33][CH2:32][CH2:31][N:30]3[CH:29]=1>>[CH:24]([Si:17]([CH:18]([CH3:20])[CH3:19])([CH:21]([CH3:23])[CH3:22])[O:16][CH2:15][C:10]1[CH:11]=[CH:12][CH:13]=[C:14]2[C:9]=1[NH:8][CH:7]=[C:6]2[C:4]1[C:3](=[O:27])[NH:43][C:41](=[O:42])[C:40]=1[C:28]1[C:38]2=[C:39]3[C:34](=[CH:35][CH:36]=[CH:37]2)[CH2:33][CH2:32][CH2:31][N:30]3[CH:29]=1)([CH3:26])[CH3:25]

参加物

3

反応物 2

HCID 16742967(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamideHCID 69742759oxo-(7-triisopropylsilanyloxymethyl-1H-indol-3-yl)-acetic acid methyl ester

生成物 1

HCID 697429363-(7-(Triisopropylsilyloxy)methyl-1H-indol-3-yl)-4-(5,6-dihydro-4H-pyrrolo [3,2,1-ij]quinolin-1-yl)-pyrrole-2,5-dione

実験手順

Beginning with 7-((triisopropylsilyloxy)methyl)indole-3-glyoxylic acid methyl ester and 2-(5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetamide, the title compound was prepared essentially as described in Example 1.

出典と根拠

ORDレコード
ord-441a983b41dc46e69a910d2dc9132a95
出典データセット
uspto-grants-2005_03
特許番号
US06867198B2

反応ノート

読み込み中…