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HRID 984282作成日:2026年10月26日

Tert-butyl 4-(4-chlorophenylamino)piperidine-1-carboxylate → 1-(tert-butoxycarbonyl)-4-[N-(4-chlorophenyl)-N-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]amino]piperidine

https://huagongshe.com/reaction/984282

反応式

関与物質

役割名称HCID仕込み量
反応物Tert-butyl 4-(4-chlorophenylamino)piperidine-1-carboxylateHCID 1491503—
反応物4-Chloromethyl-2-(3,4,5-trimethoxyphenyl) pyridineHCID 12019237—
生成物1-(tert-butoxycarbonyl)-4-[N-(4-chlorophenyl)-N-[[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl]amino]piperidineHCID 22557808—

反応手順

1-(tert-Butoxycarbonyl)-4-[(4-chlorophenyl)amino]piperidine (621 mg) and 4-chloromethyl-2-(3,4,5-trimethoxyphenyl)pyridine (588 mg) was treated in the same manner as described in Example 9 to give light yellow amorphous of the title compound.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06867221B2
出典データセットuspto-grants-2005_03
ORD IDord-4970b49e6dc043c2b5abd2e279b46a79
出典メモuspto-grants-2005_03