2,5-Dimethoxyphenylboronic acid → (E)-ethyl 3-(2',5'-dimethoxy-biphenyl-4-yl)-but-2-enoate

反応式

Br[C:2]1[CH:7]=[CH:6][C:5](/[C:8](/[CH3:15])=[CH:9]/[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1.[CH3:16][O:17][C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][C:19]=1B(O)O>>[CH3:16][O:17][C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][C:19]=1[C:2]1[CH:7]=[CH:6][C:5](/[C:8](/[CH3:15])=[CH:9]/[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1

参加物

反応物 2

HCID 27343422,5-Dimethoxyphenylboronic acid

HCID 15933615(E)-ethyl 3-(4-bromophenyl)-but-2-enoate

生成物 1

HCID 22557594(E)-ethyl 3-(2',5'-dimethoxy-biphenyl-4-yl)-but-2-enoate

実験手順

The colourless oil, (E)-ethyl 3-(2′,5′-dimethoxy-biphenyl-4-yl)-but-2-enoate was prepared from (E)-ethyl 3-(4-bromophenyl)-but-2-enoate (example 50a) and 2,5-dimethoxyphenyl boronic acid by a procedure analogous to that described in example 52a.

出典と根拠

ORDレコード: ord-8105724f23a844008f1e0e78700f1a3e
出典データセット: uspto-grants-2005_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06867218B2

反応ノート

読み込み中…