3,5-Dichlorophenylboronic acid → (E)-ethyl 3-(3',5'-dichloro-biphenyl-4-yl)-but-2-enoate

反応式

I[C:2]1[CH:7]=[CH:6][C:5](/[C:8](/[CH3:15])=[CH:9]/[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1.[Cl:16][C:17]1[CH:18]=[C:19](B(O)O)[CH:20]=[C:21]([Cl:23])[CH:22]=1>>[Cl:16][C:17]1[CH:18]=[C:19]([C:2]2[CH:7]=[CH:6][C:5](/[C:8](/[CH3:15])=[CH:9]/[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=2)[CH:20]=[C:21]([Cl:23])[CH:22]=1

参加物

反応物 2

HCID 27343313,5-Dichlorophenylboronic acid

HCID 11438459(E)-ethyl 3-(4-iodophenyl)-but-2-enoate

生成物 1

HCID 22557629(E)-ethyl 3-(3',5'-dichloro-biphenyl-4-yl)-but-2-enoate

実験手順

The colourless solid (E)-ethyl 3-(3′,5′-dichloro-biphenyl-4-yl)-but-2-enoate was prepared from (E)-ethyl 3-(4-iodophenyl)-but-2-enoate (example 91 a) and 3,5-dichlorobenzene boronic acid by a procedure analogous to that described in example 52a.

出典と根拠

ORDレコード: ord-49f8e9824f994fe4ba2e5052b378ccae
出典データセット: uspto-grants-2005_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06867218B2

反応ノート

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