2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-({6-[2-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-2-hydroxyethyl]pyridin-2-yl}amino)thiophene-3-carboxamide

HRID 98524

反応式

[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([CH2:8][CH:9]([OH:10])[CH:11]2[CH2:12][CH2:13][S:14](=[O:17])(=[O:18])[CH2:15][CH2:16]2)[n:7]1.[NH2:19][c:20]1[s:21][c:22](-[c:28]2[c:29]([F:39])[cH:30][c:31]([C:35]([CH3:36])([CH3:37])[OH:38])[cH:32][c:33]2[F:34])[cH:23][c:24]1[C:25](=[O:26])[NH2:27]>>[c:2]1([NH:19][c:20]2[s:21][c:22](-[c:28]3[c:29]([F:39])[cH:30][c:31]([C:35]([CH3:36])([CH3:37])[OH:38])[cH:32][c:33]3[F:34])[cH:23][c:24]2[C:25](=[O:26])[NH2:27])[cH:3][cH:4][cH:5][c:6]([CH2:8][CH:9]([OH:10])[CH:11]2[CH2:12][CH2:13][S:14](=[O:17])(=[O:18])[CH2:15][CH2:16]2)[n:7]1