M-Cresol → Methyl-1,4-benzoquinone
反応式
[CH:1]1[C:6]([OH:7])=[CH:5][CH:4]=[CH:3][C:2]=1[CH3:8].[OH:9]O>C(O)(=O)C>[CH3:8][C:2]1[C:3](=[O:9])[CH:4]=[CH:5][C:6](=[O:7])[CH:1]=1参加物
4
反応条件
- 温度
- 55 °C
実験手順
A mixture of m-cresol (5 mmol) and Ti-superoxide catalyst (125 mg, 20% w/w) in acetic acid (5 ml) was heated with stirring at 50-60° C. under inert atmosphere. To this reaction mixture was added aq. 30% H2O2 (20 mmol) drop wise over 15 min. and heated for 1 h. The catalyst was recovered by simple filtration and 2-methyl-1,4-benzoquinone formed (99%) was separated by chromatographic purification.
後処理
- temperaturewas heated
- temperatureheated for 1 h
- filtrationThe catalyst was recovered by simple filtration and 2-methyl-1,4-benzoquinone
- customformed (99%)
- customwas separated by chromatographic purification
出典と根拠
- ORDレコード
- ord-77ae33e3a77248feb8c6754766aea5ff
- 出典データセット
- uspto-grants-2005_03
- 特許番号
- US06872857B1
反応ノート
読み込み中…