116174-33-5 → 7-(Methylsulfanyl)-1,2,3,4-tetrahydronaphthalen-1-one
反応式
[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][CH2:11][C:12]([OH:14])=O)=[CH:5][CH:4]=1>O>[CH3:1][S:2][C:3]1[CH:4]=[C:5]2[C:6]([CH2:9][CH2:10][CH2:11][C:12]2=[O:14])=[CH:7][CH:8]=1参加物
3
反応条件
- 温度
- 60 °C
実験手順
0.055 mol of the compound obtained in Step B and 100 g of polyphosphoric acid are introduced into a 500 ml round-bottomed flask. The reaction mixture is heated at 60° C. for 3 hours and is then cooled and poured into water. Extraction with ethyl ether is carried out; the organic phase is washed with water, dried over MgSO4 and evaporated under reduced pressure. The residue obtained is purified by chromatography on silica gel. Yellow oil
後処理
- temperatureis then cooled
- extractionExtraction with ethyl ether
- washthe organic phase is washed with water
- dry with materialdried over MgSO4
- customevaporated under reduced pressure
- customThe residue obtained
- customis purified by chromatography on silica gel
出典と根拠
- ORDレコード
- ord-70469e88b92c4351b6b7e9591a0df28d
- 出典データセット
- uspto-grants-2005_03
- 特許番号
- US06872851B1
反応ノート
読み込み中…