関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Isopropanol | HCID 3776 | — |
| 反応物 | Sodium borohydride | HCID 4311764 | — |
| 反応物 | Benzenepropanal, alpha,alpha,3-trimethyl- | HCID 13797308 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | Majantol | HCID 175948 | — |
反応手順
44 g of 2,2-dimethyl-3-(3-methylphenyl)-propionaldehyde (according to Example 3) were added in small portions under argon and at 20° C. to a pre-mix of 150 ml of isopropanol and 3.8 g of sodium borohydride. The entire mixture was stirred for 24 hours at 20° C. Excess sodium borohydride was then decomposed by the dropwise addition of 2N HCl. The reaction mixture was then taken up in 150 ml of diethyl ether and extracted with water, 2N NaOH and, again, with water.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04710316 |
|---|
| 出典データセット | uspto-grants-1987_12 |
|---|
| ORD ID | ord-c3daf21f1f544a39a01ecd90a322c1bf |
|---|
| 出典メモ | uspto-grants-1987_12 |
|---|
