化工社化工社 化学情報印刷レポート · 研究参考用
Enprofylline → 3-Propyl-6-thioxanthine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Enprofylline | HCID 1676 | — |
| 反応物 | Phosphorus sulfide (P2S5) | HCID 14817 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 3-Propyl-6-thioxanthine | HCID 14014540 | — |
反応手順
A suspension of 9.32 g. (48 mM.) of 3-propylxanthine in 80 ml. of pyridine, was treated with 17.33 g. (78 mM.) of phosphorus pentasulfide in 80 ml. of pyridine, and worked up analogously to Example I. 8.9 g. of 3-propyl-6-thioxanthine was obtained. Recrystallization from methanol-acetone gave 7.4 g. (59% yield) of needles with a melting point of 249°-250° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04710503 |
| 出典データセット | uspto-grants-1987_12 |
| ORD ID | ord-d2a3177f855d42d6a0dcc040f2a3c249 |
| 出典メモ | uspto-grants-1987_12 |