関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Imidazole | HCID 795 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | o-Toluenesulfonyl chloride, 5-nitro- | HCID 8457 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 1-(5-Nitro-2-methyl-phenylsulfonyl)-imidazole | HCID 685057 | 63.6% |
反応手順
2.36 g of 5-nitro-2-methyl-phenylsulfonyl chloride (0.01 mol) and 1.36 g of imidazole (0.02 mol) were dissolved in 15 ml of pyridine, and the mixture was stirred at 50° C. for 3 hours to react. After the reaction, the reaction mixture was poured into water, and extracted with chloroform. The chloroform layer was washed with water and dehydrated. Evaporation of chloroform gave 1.70 g of 1-(5-nitro-2-methyl-phenylsulfonyl)-imidazole of the m.p. 119°-120° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04710509 |
|---|
| 出典データセット | uspto-grants-1987_12 |
|---|
| ORD ID | ord-fcb44b4c21584b2e92d076268a6bba5c |
|---|
| 出典メモ | uspto-grants-1987_12 |
|---|
