3-(5-Nitrofuran-2-yl)prop-2-enal → 3-(6-Methoxy-3-pyridyl)-2-propenoic acid [3-(5-nitro-2-furyl)-2-propen-1-ylidene]hydrazide

HRID 986223ノート

反応式

HRID 986223 の反応式
[CH3:1][O:2][C:3]1[N:8]=[CH:7][C:6]([CH:9]=[CH:10][C:11]([NH:13][NH2:14])=[O:12])=[CH:5][CH:4]=1.[N+:15]([C:18]1[O:22][C:21]([CH:23]=[CH:24][CH:25]=O)=[CH:20][CH:19]=1)([O-:17])=[O:16]>CO>[N+:15]([C:18]1[O:22][C:21]([CH:23]=[CH:24][CH:25]=[N:14][NH:13][C:11](=[O:12])[CH:10]=[CH:9][C:6]2[CH:7]=[N:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[CH:20][CH:19]=1)([O-:17])=[O:16]

参加物

4

反応物 2

HCID 158633-(5-Nitrofuran-2-yl)prop-2-enalHCID 704352203-(6-Methoxy-3-pyridyl)-2-propenoic acid hydrazide

生成物 1

HCID 542876343-(6-Methoxy-3-pyridyl)-2-propenoic acid [3-(5-nitro-2-furyl)-2-propen-1-ylidene]hydrazide

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

To a lukewarm solution of 0.85 g (4.4. mmol) of 3-(6-methoxy-3-pyridyl)-2-propenoic acid hydrazide in 50 ml of methanol, 0.75 g (4.5 mmol) of 3-(5-nitro-2-furyl)-2-propenal is added. A solid crystallizes slowly in the resulting homogenous solution. After the mixture has been stirred for several hours, these crystals are drained, washed with methanol and ether and dried under reduced pressure at 100° C. for 8 h.

後処理

  1. customA solid crystallizes slowly in the resulting homogenous solution
  2. washwashed with methanol and ether
  3. customdried under reduced pressure at 100° C. for 8 h.

出典と根拠

ORDレコード
ord-66680e05d6804ff5bb58b7465d38ba45
出典データセット
uspto-grants-1987_12
特許番号
US04711892

反応ノート

読み込み中…