2,6-Difluorobenzoyl isocyanate → HCID 13711427、化合物

反応式

[Cl:1][C:2]1[CH:3]=[C:4]([C:10]([F:13])([F:12])[F:11])[C:5]([F:9])=[C:6]([CH:8]=1)[NH2:7].[F:14][C:15]1[CH:25]=[CH:24][CH:23]=[C:22]([F:26])[C:16]=1[C:17]([N:19]=[C:20]=[O:21])=[O:18]>>[Cl:1][C:2]1[CH:3]=[C:4]([C:10]([F:13])([F:11])[F:12])[C:5]([F:9])=[C:6]([NH:7][C:20]([NH:19][C:17](=[O:18])[C:16]2[C:22]([F:26])=[CH:23][CH:24]=[CH:25][C:15]=2[F:14])=[O:21])[CH:8]=1

参加物

反応物 2

HCID 27333692,6-Difluorobenzoyl isocyanate

HCID 136718565-Chloro-2-fluoro-3-trifluoromethylaniline

生成物 1

HCID 13711427HCID 13711427、化合物収率 69.2%

実験手順

The product was prepared from 5-chloro-2-fluoro-3-trifluoromethylaniline (0.5 g) and 2,6-difluorobenzoylisocyanate (0.4 g) by operating according to the process of Example 1 to obtain the product 0.6 g. (m.p. 187°-189° C.)

出典と根拠

ORDレコード: ord-00c6126d9031443cb52cb2673fd31e84
出典データセット: uspto-grants-1987_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04713396

反応ノート

読み込み中…