Sodium Hydroxide → 7-Thienylamino-1H-pyrazolo[4,3-b]pyridine

関与物質

反応手順

Ethyl 7-thienylamino-1H-pyrazolo[4,3-b]pyridine-6-carboxylate (0.600 g) was converted to the corresponding acid by heating under reflux with a 2% sodium hydroxide solution in ethanol (50 ml). The ethanol was removed under reduced pressure and the residue diluted with water (5 ml) and acidified to pH5 with dilute hydrochloric acid. The resulting acid was filtered off and dried, mp 255°-259° C.

情報源と証拠