Dimethylamine → HCID 13670626、化合物
反応式
Cl[S:2]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[N:12]=[C:13]3[N:18]=[CH:17][CH:16]=[CH:15][N:14]3[CH:19]=2)=[CH:7][CH:6]=1)(=[O:4])=[O:3].[CH3:20][NH:21][CH3:22]>O>[CH3:20][N:21]([CH3:22])[S:2]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[N:12]=[C:13]3[N:18]=[CH:17][CH:16]=[CH:15][N:14]3[CH:19]=2)=[CH:7][CH:6]=1)(=[O:4])=[O:3]参加物
4
反応条件
- 温度
- 50 °C
実験手順
2.9 g (0.01 mol) of 2-(4-Chlorosulphonyl-phenyl)-imidazo[1,2-a]pyrimidine are suspended in 60 ml of a 40% solution of dimethylamine in water. The mixture is heated to 50° C. for 30 minutes, diluted with 50 ml of water, extracted with ethyl acetate, then the ethyl acetate extract is dried and evaporated to dryness. The residue is recrystallised from dimethylformamide.
後処理
- extractionextracted with ethyl acetate
- extractionthe ethyl acetate extract
- customis dried
- customevaporated to dryness
- customThe residue is recrystallised from dimethylformamide
出典と根拠
- ORDレコード
- ord-5bb0c2d4c87d40f28ad2f635f683bf6d
- 出典データセット
- uspto-grants-1987_12
- 特許番号
- US04716169
反応ノート
読み込み中…