2,3,4-Trimethoxybenzaldehyde → 6,7,8-Trimethoxynaphthalene-2-carbonitrile

反応式

[CH3:1][O:2][C:3]1[C:10]([O:11][CH3:12])=[C:9]([O:13][CH3:14])[CH:8]=[CH:7][C:4]=1[CH:5]=O.CO[CH:17](OC)[CH2:18][CH2:19][C:20]#[N:21]>>[CH3:14][O:13][C:9]1[CH:8]=[C:7]2[C:4](=[C:3]([O:2][CH3:1])[C:10]=1[O:11][CH3:12])[CH:5]=[C:19]([C:20]#[N:21])[CH:18]=[CH:17]2

参加物

反応物 2

HCID 750062,3,4-Trimethoxybenzaldehyde

HCID 845584,4-Dimethoxybutyronitrile

生成物 1

HCID 218916206,7,8-Trimethoxynaphthalene-2-carbonitrile

実験手順

2,3,4-Trimethoxybenzaldehyde (9.8 g) and 3-cyano-propionaldehyde dimethylacetal (6.35 mL) were treated under the same conditions as in Preparation Example 1 to obtain the title compound.

出典と根拠

ORDレコード: ord-4ef3fd05e5154fe5b338eb507e9ad2a2
出典データセット: uspto-grants-2003_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06632810B2

反応ノート

読み込み中…