2-Bromo-N-phenylacetamide → N-phenyl-4-[4-(4-fluorophenyl)methylphenyl]-1-piperidinacetamide

HRID 989

反応式

HRID 989 の反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([CH:15]3[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]3)=[CH:11][CH:10]=2)=[CH:4][CH:3]=1.[C:21]1([NH:27][C:28](=[O:31])[CH2:29]Br)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[C:21]1([NH:27][C:28](=[O:31])[CH2:29][N:18]2[CH2:17][CH2:16][CH:15]([C:12]3[CH:13]=[CH:14][C:9]([CH2:8][C:5]4[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=4)=[CH:10][CH:11]=3)[CH2:20][CH2:19]2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

参加物

3

反応物 2

HCID 948182-Bromo-N-phenylacetamideHCID 154621204-[4-(4-Fluorophenyl)methylphenyl]piperidine

生成物 1

HCID 19694263N-phenyl-4-[4-(4-fluorophenyl)methylphenyl]-1-piperidinacetamide

実験手順

The compound (7) synthesized in Reference Example 7 and the compound (23) synthesized in Reference Example 23 were used to produce the above compound in the same way as Example 1.

後処理

  1. customto produce the above compound in the same way as Example 1

出典と根拠

ORDレコード
ord-0dbe0dca9fae46829877e914cdfc371e
出典データセット
uspto-grants-1998_03
特許番号
US05723475

関連ノート

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