Water → Pyridine-2-carbaldehyde thiosemicarbazone
反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]=O.[NH2:9][NH:10][C:11]([NH2:13])=[S:12].O>C(O)C.O>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]=[N:9][NH:10][C:11]([NH2:13])=[S:12]参加物
5
実験手順
The corresponding pyridine-2-formaldehyde (23, 23a or 28a-k, 10 mmol) was dissolved in ethanol-water (2:1 v/v, 150 mL). To the solution was added thiosemicarbazide (11 mmol). The solution was stirred for 30 min at ambient temperature. After addition of water (50 mL), the reaction mixture was stirred vigorously for 2 h at room temperature. The yellow precipitate was collected by filtration, washed with ethanol-water (1:4 v/v) and dried in vacuum to afford the corresponding pyridine-2-carboxaldehyde thiosemicarbazone (24, 24a, 29a-k).
後処理
- stirringthe reaction mixture was stirred vigorously for 2 h at room temperature
- filtrationThe yellow precipitate was collected by filtration
- washwashed with ethanol-water (1:4 v/v)
- customdried in vacuum
出典と根拠
- ORDレコード
- ord-1e741fe4ece3468793eb6392e14c75a3
- 出典データセット
- uspto-grants-2002_10
- 特許番号
- US06458816B1
反応ノート
読み込み中…