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Glyceraldehyde → Benzyl 4,5-dihydroxy-2-pentenoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Glyceraldehyde | HCID 751 | — |
| 反応物 | (Benzyloxycarbonylmethyl)triphenylphosphonium bromide | HCID 11214019 | — |
| 溶媒 | 1,2-Epoxybutane | HCID 7834 | — |
| 生成物 | Benzyl 4,5-dihydroxy-2-pentenoate | HCID 54529065 | — |
反応手順
A mixture of DL-glycerinaldehyde (4.5 g, 50 mmole) and (benzyloxycarbonylmethyl)-triphenyl-phosphoniumbromide (24.57 g, 50 mmole) in 100 ml 1,2-epoxybutane was refluxed overnight. The mixture was evaporated under vacuum and the product was isolated by silica gel column chromatography. Yield: 8 g=71%
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06458772B1 |
| 出典データセット | uspto-grants-2002_10 |
| ORD ID | ord-bf93b888e5ab4bcd9be5e6dda82bab73 |
| 出典メモ | uspto-grants-2002_10 |