4-(4-Phenoxyphenyl)piperidine → N-(2,6-diisopropylphenyl)-4-(4-phenoxyphenyl)-1-piperidinacetamide

HRID 990

反応式

HRID 990 の反応式
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]2)=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:20]([C:23]1[CH:28]=[CH:27][CH:26]=[C:25]([CH:29]([CH3:31])[CH3:30])[C:24]=1[NH:32][C:33](=[O:36])[CH2:34]Br)([CH3:22])[CH3:21]>>[CH:20]([C:23]1[CH:28]=[CH:27][CH:26]=[C:25]([CH:29]([CH3:30])[CH3:31])[C:24]=1[NH:32][C:33](=[O:36])[CH2:34][N:17]1[CH2:18][CH2:19][CH:14]([C:11]2[CH:12]=[CH:13][C:8]([O:1][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=3)=[CH:9][CH:10]=2)[CH2:15][CH2:16]1)([CH3:21])[CH3:22]

参加物

3

反応物 2

HCID 110759844-(4-Phenoxyphenyl)piperidineHCID 12149064Acetamide, N-[2,6-bis(1-methylethyl)phenyl]-2-bromo-

生成物 1

HCID 19694264N-(2,6-diisopropylphenyl)-4-(4-phenoxyphenyl)-1-piperidinacetamide

実験手順

The compound (4) synthesized in Reference Example 4 and the compound (24) synthesized in Reference Example 24 were used to produce the above compound in the same way as Example 1.

後処理

  1. customto produce the above compound in the same way as Example 1

出典と根拠

ORDレコード
ord-d49e044d91ba41819787fce94b25dafb
出典データセット
uspto-grants-1998_03
特許番号
US05723475

関連ノート

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