1-Bromopropane → HCID 70149959、化合物
反応式
[NH:1]1[CH:5]2[CH2:6][CH2:7][CH2:8][CH2:9][CH:4]2[NH:3][C:2]1=[S:10].[Br:11][CH2:12][CH2:13][CH3:14]>C(O)C>[BrH:11].[CH2:12]([S:10][C:2]1[NH:3][CH:4]2[CH2:9][CH2:8][CH2:7][CH2:6][CH:5]2[N:1]=1)[CH2:13][CH3:14]参加物
4
実験手順
1 g of octahydro 2H-benzimidazol-2-thione and 1.3 ml of bromopropane in 20 ml of ethanol are heated under reflux until complete dissolution is obtained. The solvent is evaporated off under reduced pressure, the residue is taken up in a minimum amount of dichloromethane, isopropyl ether is added, the solvents are evaporated off under reduced pressure, the residue is recrystallized from isopropyl ether, the expected product is separated off and dried with a yield of 95%.
後処理
- temperatureunder reflux until complete dissolution
- customis obtained
- customThe solvent is evaporated off under reduced pressure
- additionis added
- customthe solvents are evaporated off under reduced pressure
- customthe residue is recrystallized from isopropyl ether
- customthe expected product is separated off
- customdried with a yield of 95%
出典と根拠
- ORDレコード
- ord-d2747b8ff70b4a42b863385f2c5a540f
- 出典データセット
- uspto-grants-2002_10
- 特許番号
- US06459001B1
反応ノート
読み込み中…