関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 1-Bromo-3-chloropropane | HCID 8006 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Acetamide, N-(2-hydroxy-5-nitrophenyl)- | HCID 3292867 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | n-[2-(3-Chloropropoxy)-5-nitrophenyl]acetamide | HCID 18415451 | — |
反応手順
A mixture of 186.5 g (0.94 mol) of N—(2-hydroxy-5-nitrophenyl)acetamide and 142.7 g (1.03 mol) of potassium carbonate in 570 ml of dimethylformamide was heated to 30-35° C. with stirring; 444.0 g (2.82 mol) of 1-bromo-3-chloropropane were then added and heating was continued at 40° C. for 7 hours (orange-coloured suspension).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06461389B1 |
|---|
| 出典データセット | uspto-grants-2002_10 |
|---|
| ORD ID | ord-1431f11f41c74938b6e443c9084a24fd |
|---|
| 出典メモ | uspto-grants-2002_10 |
|---|
