2,2-Diphenylacetyl chloride → N-(5-Ethyl-oxazol-2-yl)-2,2-diphenyl-acetamide

反応式

[CH2:1]([C:3]1[O:7][C:6]([NH2:8])=[N:5][CH:4]=1)[CH3:2].[C:9]1([CH:15]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:16](Cl)=[O:17])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[CH2:1]([C:3]1[O:7][C:6]([NH:8][C:16](=[O:17])[CH:15]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[N:5][CH:4]=1)[CH3:2]

参加物

反応物 2

HCID 746372,2-Diphenylacetyl chloride

HCID 226610805-Ethyl-2-oxazolamine

生成物 1

HCID 9796553N-(5-Ethyl-oxazol-2-yl)-2,2-diphenyl-acetamide

実験手順

The title compound, white solid, m.p. 148-149° C. and MS: m/e=307.3 (M+H+) was prepared in accordance with the general method of example 44a from 5-ethyl-oxazol-2-ylamine and 2,2-diphenylacetic acid chloride.

出典と根拠

ORDレコード: ord-51caa13ed969411abd99880bd5a173ff
出典データセット: uspto-grants-2002_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06462198B1

反応ノート

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