Estradiol → Estradiol methyltestosterone

HRID 991390

反応式

HRID 991390 の反応式
[CH3:1][C@@:2]12[C@H:12]3[CH2:13][CH2:14][C@:15]4([CH3:22])[C@:19]([OH:21])([CH3:20])[CH2:18][CH2:17][C@H:16]4[C@@H:11]3[CH2:10][CH2:9][C:8]1=[CH:7][C:5](=[O:6])[CH2:4][CH2:3]2.C[C@@]12[C@@H](O)CC[C@H]1[C@H]1[C@@H](C3C=CC(O)=CC=3CC1)CC2.C([O-])(=O)C=C.CC(O)COC(CO)C.C(O)CCCCCCC/C=C\CCCCCCCC>C(OCC)(=O)C.CCCCCC.C(O)(C)C>[CH3:22][C@@:15]12[C@@H:19]([OH:21])[CH2:18][CH2:17][C@H:16]1[C@H:11]1[C@@H:12]([C:2]3[CH:3]=[CH:4][C:5]([OH:6])=[CH:7][C:8]=3[CH2:9][CH2:10]1)[CH2:13][CH2:14]2.[CH3:1][C@@:2]12[C@H:12]3[CH2:13][CH2:14][C@:15]4([CH3:22])[C@:19]([OH:21])([CH3:20])[CH2:18][CH2:17][C@H:16]4[C@@H:11]3[CH2:10][CH2:9][C:8]1=[CH:7][C:5](=[O:6])[CH2:4][CH2:3]2

参加物

10

反応物 6

HCID 5757EstradiolHCID 6010MethyltestosteroneHCID 25188AcrylateHCID 328812-(2-Hydroxypropoxy)-1-propanolHCID 5284499Oleyl AlcoholHCID 178527255HCID 178527255、化合物

生成物 1

HCID 9829635Estradiol methyltestosterone

試薬・触媒・溶媒 3

HCID 3776Isopropanol溶媒HCID 8058Hexane溶媒HCID 8857Ethyl Acetate溶媒3 回

実験手順

An estradiol/methyltestosterone pressure-sensitive adhesive mixture was prepared by combining 4.0 parts of methyltestosterone and 1.1 parts of estradiol in a solution of 42.3 parts of CAB-381-0.1 with 38.0 parts each of isopropyl alcohol and ethyl acetate. Then 76.5 parts of a polysiloxane adhesive (BIO-PSA® Q7-4502, a silicone in ethyl acetate; Dow Corning Corporation, Medical Products, Midland, Mich.), 48.8 parts of a polyacrylate adhesive (DURO-TAK® 87-2510, an acrylate copolymer in ethyl acetate and hexane; National Starch and Chemical Corporation, Bridgewater, N.J.), 8.0 parts of dipropylene glycol and 6.0 parts of oleyl alcohol were added and thoroughly mixed in an appropriate container until the mixture was completely homogeneous. The resulting composition had the ingredient concentrations on a dry weight percent basis (i.e., after evaporation of volatile solvents) as shown below.

後処理

  1. additionthoroughly mixed in an appropriate container until the mixture
  2. concentrationthe ingredient concentrations
  3. customon a dry weight percent basis (i.e., after evaporation of volatile solvents)

出典と根拠

ORDレコード
ord-84160a0d70d14e1087576ca7a0ef96f3
出典データセット
uspto-grants-2002_10
特許番号
US06465004B1

関連ノート

読み込み中…