Ethyl α-(acetylamino)-6-quinolinepropanoate → HCID 21925070、化合物

HRID 991447ノート

反応式

HRID 991447 の反応式
C([O:3][C:4](=[O:21])[CH:5]([CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[CH:14]2)[NH:6]C(=O)C)C>Cl>[N:17]1[C:18]2[C:13](=[CH:12][C:11]([CH2:10][CH:5]([C:4]([OH:21])=[O:3])[NH2:6])=[CH:20][CH:19]=2)[CH:14]=[CH:15][CH:16]=1

参加物

3

反応物 1

HCID 21925091Ethyl α-(acetylamino)-6-quinolinepropanoate

生成物 1

HCID 21925070HCID 21925070、化合物

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

実験手順

N-Acetyl β-(6-quinolinyl)-D,L-alanine ethyl ester (728 mg, 2.55 mmol) was heated at reflux in 6N HCl (20 mL). After 20 h, the reaction mixture was concentrated to dryness and the residue was dried in vacuo to provide the title compound, which was used directly in the next reaction.

後処理

  1. concentrationthe reaction mixture was concentrated to dryness
  2. customthe residue was dried in vacuo

出典と根拠

ORDレコード
ord-66f1164eb239417e88d52c876a97e392
出典データセット
uspto-grants-2002_10
特許番号
US06465433B1

反応ノート

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