4-Bromophenol → 4-Bromophenyl dichlorophosphate
反応式
[P:1]([Cl:5])(Cl)([Cl:3])=[O:2].[Br:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1>>[P:1]([Cl:5])([Cl:3])(=[O:2])[O:13][C:10]1[CH:11]=[CH:12][C:7]([Br:6])=[CH:8][CH:9]=1参加物
3
実験手順
Phosphorous oxychloride is reacted with a para-bromophenol moiety to form para-bromophenyl phosphorodichloridate. Without purification, the para-bromophenyl phosphorodichloridate is contacted with alanine methyl ester to produce para-bromophenyl methoxyalaninyl phosphorochloridate. Without purification, the para-bromophenyl methoxyalaninyl phosphorochloridate is reacted with AZT.
出典と根拠
- ORDレコード
- ord-9fcd662047fe45f7b7d9868ad265af88
- 出典データセット
- uspto-grants-2002_10
- 特許番号
- US06465641B1
反応ノート
読み込み中…