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Ethylbenzene → 1-Phenylethanol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethylbenzene | HCID 7500 | — |
| 反応物 | N-Hydroxyphthalimide | HCID 10665 | — |
| 反応物 | Nitric Oxide | HCID 145068 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 1-Phenylethanol | HCID 7409 | 18% |
| 生成物 | 1-Nitroethylbenzene | HCID 23618 | 14% |
反応手順
Into a flask, 1 mmole of ethylbenzene, 0.05 mmole of N-hydroxyphthalimide and 5 ml of acetic acid were added to mix and the flask was equipped with a gas bag (about 1L)of nitrogen monoxide NO. The mixture was reacted for 8 hours at 100° C. with stirring. The reaction products were analyzed by gas chromatography, and, as a result, the conversion of ethylbenzene was 85%, and 1-nitroethylbenzene (yield 14%), 1-hydroxyethylbenzene (yield 18%) and 1-acetyloxyethylbenzene (yield 30%) were formed.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06468487B1 |
| 出典データセット | uspto-grants-2002_10 |
| ORD ID | ord-c458f446724549468ddfe965d5681074 |
| 出典メモ | uspto-grants-2002_10 |