化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Acid → 3-Nitrotricyclo(3.3.1.13,7)decane-1-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | N-Hydroxyphthalimide | HCID 10665 | — |
| 反応物 | 1-Adamantanecarboxylic acid | HCID 13235 | — |
| 生成物 | 3-Nitrotricyclo(3.3.1.13,7)decane-1-carboxylic acid | HCID 39239 | 80% |
反応手順
Into a flask, 1 mmole of 1-carboxyadamantane, 0.1 mmole of N-hydroxyphthalimide and 6 ml of acetic acid were added to mix. The mixture was purged by nitrogen monoxide NO (about 1L) and oxygen O2 (about 1L), and then reacted for 20 hours at 110° C. with stirring. The reaction products were analyzed by gas chromatography, and, as a result, the conversion of 1-carboxyadamantane was 90%, and 1-carboxy-3-nitroadamantane (yield 80%) was formed.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06468487B1 |
| 出典データセット | uspto-grants-2002_10 |
| ORD ID | ord-dfd3540c043044058646b3a81bad990c |
| 出典メモ | uspto-grants-2002_10 |