Diethyl Ether → 2-Bromo-4-chlorobenzenediazonium tetrafluoroborate

HRID 992484

反応式

HRID 992484 の反応式
[Br:1][C:2]1[CH:8]=[C:7]([Cl:9])[CH:6]=[CH:5][C:3]=1[NH2:4].[H+].[B-:11]([F:15])([F:14])([F:13])[F:12].[N:16]([O-])=O.[Na+].C(OCC)C>CCO>[F:12][B-:11]([F:15])([F:14])[F:13].[Br:1][C:2]1[CH:8]=[C:7]([Cl:9])[CH:6]=[CH:5][C:3]=1[N+:4]#[N:16]

参加物

6

反応物 4

HCID 3283Diethyl EtherHCID 28118Tetrafluoroboric acidHCID 701102-Bromo-4-chloroanilineHCID 23668193Sodium Nitrite

生成物 1

HCID 184127642-Bromo-4-chlorobenzenediazonium tetrafluoroborate収率 96%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A solution of 2-bromo-4-chloroaniline (10.0 g, 48.4 mmol) and HBF4 in EtOH (60 mL) kept at 0° C. was treated with an aqueous solution (20 mL) of NaNO2 (3.34g, 48.4 mmol). After completion of the addition, diethyl ether (200 mL) was added to the mixture. The solid was collected by filtration, washed with water and dried under high vacuum affording the title compound (14.2 g, 96%) as white crystals.

後処理

  1. customkept at 0° C.
  2. additionwas added to the mixture
  3. filtrationThe solid was collected by filtration
  4. washwashed with water
  5. customdried under high vacuum

出典と根拠

ORDレコード
ord-455616b784b7483eb55eb365e0f0b005
出典データセット
uspto-grants-2002_10
特許番号
US06469042B1

関連ノート

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