Hexahydro-1,4-diazepine → N,N'-bis[[1-Methyl-3-(3,4,5-trimethoxy-phenyl)pyrazol-5-yl]methyl]homopiperazine

HRID 993012ノート

反応式

HRID 993012 の反応式
Cl[CH2:2][C:3]1[N:7]([CH3:8])[N:6]=[C:5]([C:9]2[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=2)[CH:4]=1.[NH:21]1[CH2:27][CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1>>[CH3:8][N:7]1[C:3]([CH2:2][N:21]2[CH2:27][CH2:26][CH2:25][N:24]([CH2:2][C:3]3[N:7]([CH3:8])[N:6]=[C:5]([C:9]4[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=4)[CH:4]=3)[CH2:23][CH2:22]2)=[CH:4][C:5]([C:9]2[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=2)=[N:6]1

参加物

3

反応物 2

HCID 68163Hexahydro-1,4-diazepineHCID 184084865-Chloromethyl-1-methyl-3-(3,4,5-trimethoxy-phenyl)pyrazole

生成物 1

HCID 10282613N,N'-bis[[1-Methyl-3-(3,4,5-trimethoxy-phenyl)pyrazol-5-yl]methyl]homopiperazine

実験手順

5-Chloromethyl-1-methyl-3-(3,4,5-trimethoxy-phenyl)pyrazole (119 mg) and homopiperazine (20 mg) were reacted in the same manner in Example 1 to obtain the title compound as a free base.

出典と根拠

ORDレコード
ord-7cf00be08ab44a738c727ec51cbd2f09
出典データセット
uspto-grants-2002_10
特許番号
US06472386B1

反応ノート

読み込み中…