3-Aminopyridine (HCID 10009)

개요

RN given refers to parent cpd

이름 및 식별자

우선 이름: 3-Aminopyridine
IUPAC: pyridin-3-amine
현지명: 3-아미노피리딘
영어명: 3-Aminopyridine
분자식: C5H6N2
분자량: 94.11

이름 및 동의어

3-AMINOPYRIDINE462-08-83-Pyridinaminem-Aminopyridinebeta-AminopyridineDTXSID9047461UN267169JE8P2L84NSC-15040DTXCID7027461UN-2671RefChem:911164

이름 더 보기

3-아미노피리딘3-아미노피리딘(3-AMINOPYRIDINE)스쿠아르산462-08-0462-08-03APYNSC 15040AKOS 909773-Pyridylamin

207-322-2pyridin-3-amine3-PyridylamineAmino-3 pyridinePyridine, 3-amino-3-amino pyridinepyridin-3-ylamine.beta.-Aminopyridine

데이터베이스 식별자

CAS: 462-08-8
PubChem CID: 10009
DTXSID: DTXSID9047461
ChEMBL: CHEMBL25541
UNII: 69JE8P2L84
EC Number: 207-322-2
Nikkaji: J1.535K

물성

구조 계산 물성

XLogP: 0.1
극성 표면적: 38.9 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 2
회전 가능 결합 수: 0
무거운 원자 수: 7
형식 전하: 0
복잡도: 54

실험 및 물리화학적 성질

Chemical ClassesNitrogen Compounds -> Pyridines

SpringerMaterials PropertiesMolecular structure

LogP0.05

Flash Point190.4 °F

Boiling Point483.8 °F

Melting Point147.2 °F

물리화학적 성질

녹는점: 60 · 60-63 °C(lit.)
끓는 점: 248 °C · 248 °C(lit.)
밀도: 1.0308 · 1.0308 (estimate)
굴절률: 1.556 · 1.5560 (estimate)
인화점: 124 °C · 124 °C
저장 조건: Poison room
용해도: 1000 g/L · >1000g/L
물리적 상태: 액체
산도 계수 (pKa): 6.04 · 6.04(at 25℃)
색상: 무색~황색으로 투명함
수소이온지수(pH): 10 · 10 (100g/l, H2O, 20℃)
수용성: 물에 용해되며 알코올, 벤젠에도 용해됩니다.
Merck: 14 · 14,473
BRN: 105692 · 105692
InChI: 1S/C5H6N2/c6-5-2-1-3-7-4-5/h1-4H,6H2
InChIKey: CUYKNJBYIJFRCU-UHFFFAOYSA-N
SMILES: Nc1cccnc1
LogP: 0.11 · 0.110
NIST: 3 · 3-Pyridinamine(462-08-8)
EPA: 3 · 3-Aminopyridine (462-08-8)

화학적 성질

white to light yellow crystal powder

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H300 (15%): Fatal if swallowed [Danger Acute toxicity, oral]

P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 60 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 4건

Chemical: 3-Pyridinamine

3-Pyridinamine is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 3-Pyridinamine are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 29-07-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/16757

3-Aminopyridine: Does not have an individual approval but may be used under an appropriate group standard

Hazards Summary · 1건

Causes convulsions in intracerebral lethal-dose studies of mice; Intravenous LD50 (mouse) = 24 mg/kg; [RTECS] Readily absorbed through skin; [NTP] A skin, eye, and mucous membrane irritant; Toxic by ingestion; [ToxPlanet: OSHA] A skin and strong eye irritant; Harmful by skin absorption; Toxic by ingestion; Oral LD50 (rat) = 50-200 mg/kg; [Alfa Aesar MSDS] See 2-Aminopyridine.

Hazard Classes and CategoriesAcute Tox. 2 (15%)

독성 정보

Adverse EffectsNeurotoxin - Other CNS neurotoxin

안전 데이터

wgk: 3
tsca: TSCA listed
rtecs: US1650000
ridadr: UN 2671 (AMINOPYRIDINES (o-, m-, p,))
독성: LD50 ipr-mus: 28 mg/kg JMCMAR 8,296,65
HS 번호: 29333999
risk_code: 23/24/25-33-36/37/38-25
hazard_code: T,Xi
safety_code: 36/37/39-45-37/39-28B-26
포장분류: II
위험 등급: 6.1
기존화학 물질: KE-29926
F 고인화성물질: 3-8-9-23
위험 참고 사항: Toxic/Irritant
Hazard Classifications: Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 3 OralEye Irrit. 2Skin Irrit. 2STOT RE 2STOT SE 3
스토리지 클래스: 6.1A - Combustible acute toxic Cat. 1 and 2very toxic hazardous materials

화학 및 산업

용도 및 제조

UsesUsed to make pharmaceuticals and dyes; [Merck Index] Also used to make agrochemicals and as a plant growth regulator; [NTP]

U.S. Production2023: 250,000 - <550,000 lb

Industry UsesIntermediate

General Manufacturing Information · 2건

All Other Basic Organic Chemical Manufacturing

3-Pyridinamine: ACTIVE

응용 분야 · 1건

용도3-Aminopyridine is a monosubstituted pyridine that shows convulsive effects on cortical Neurons. 3-Aminopyridine is used in the synthesis of of organic ligand 3-Pyridylnicotinamide. 3-Aminopyridine al ong with other aminopyridines have been shown to reversibly block voltage-dependent potassium channels,

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

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上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

盐城华弘化工有限公司15366451979

INTATRADE GmbH+49 3493/605464 · [email protected]

연결된 노트

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3-아미노피리딘

기본 정보

개요