기본 정보
- CAS
40925-28-8- 표준 SMILES
NC(=O)c1ncn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)n1- InChIKey
SDWIOXKHTFOULX-AFCXAGJDSA-N- 분자식
- C8H13N4O8P
- 평균 분자량
- 324.18 g/mol
- 단동위원소 질량
- 324.04710038
이름 및 식별자
- 우선 이름
- Ribavirin monophosphate
- IUPAC
- [(2R,3S,4R,5R)-5-(3-carbamoyl-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
- 현지명
- 리바비린-5'-포스페이트
- 영어명
- ribavirin-5'-phosphate
- 분자식
- C8H13N4O8P
- 분자량
- 324.19
이름 및 동의어
Ribavirin monophosphate40925-28-8Ribavirin-5'-phosphateRibavirin 5'-monophosphateRibavirin 5'-phosphate1-(5-O-Phosphono-beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamideO9FVV27P11CHEBI:45490DTXSID20193928NSC-274937RefChem:930750DTXCID60116419
이름 더 보기
리바비린-5'-포스페이트Ribavirin 5'-monophosphate sodium saltResorcinol Impurity 38Ribavirin-5′,-monophosphate1H-1,2,4-Triazole-3-carboxamide, 1-(5-O-phosphono-β-D-ribofuranosyl)-[(2R,3S,4R,5R)-5-(3-carbamoyl-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate((2R,3S,4R,5R)-5-(3-carbamoyl-1H-1,2,4-triazol-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
1 beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-phosphate(((2R,3S,4R,5R)-5-(3-carbamoyl-1H-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl)methoxy)phosphonic acidVirazole 5'-phosphateICN 38471beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-phosphate1H-1,2,4-Triazole-3-carboxamide, 1-(5-O-phosphono-.beta.-D-ribofuranosyl)-RVPUNII-O9FVV27P11
물성
구조 계산 물성
- XLogP
- -3.5
- 극성 표면적
- 190 Ų
- 수소 결합 공여자 수
- 5
- 수소 결합 수용자 수
- 10
- 회전 가능 결합 수
- 5
- 무거운 원자 수
- 21
- 형식 전하
- 0
- 복잡도
- 446
물리화학적 성질
- 끓는 점
- 767.3 · 767.3±70.0 °C(Predicted)
- 밀도
- 2.33 · 2.33±0.1 g/cm3(Predicted)
- 산도 계수 (pKa)
- 1.86 · 1.86±0.10(Predicted)
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
응용 분야
용도Ribavirin Monophosphate, is a metabolite of Ribavirin (R414475), a urine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.
공급사5 곳
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TLC梯尔希（南京）药物研发有限公司18012923235 · [email protected]
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