기본 정보
- CAS
13465-08-2- 표준 SMILES
NO.O=[N+]([O-])O- InChIKey
NILJXUMQIIUAFY-UHFFFAOYSA-N- 분자식
- H4N2O4
- 평균 분자량
- 96.04 g/mol
- 단동위원소 질량
- 96.01710661
개요
Hydroxylammonium nitrate (HAN) is the salt of hydroxylamine and nitric acid. It is being developed as a potential rocket propellant and is sometimes used in nuclear reprocessing as a plutonium reductant. Nitrite is a toxic compound known to cause methemoglobinemia. (L1137, L1628)
이름 및 식별자
- 우선 이름
- Hydroxylammonium nitrate
- IUPAC
- hydroxylamine;nitric acid
- 현지명
- 히드록실아민 질산
- 영어명
- Hydroxylamine nitrate
- 분자식
- H4N2O4
- 분자량
- 96.04
이름 및 동의어
DTXSID30884613hydroxyazanium nitrateRefChem:1087090DTXCID501024044236-691-213465-08-2Hydroxylammonium nitrateHYDROXYLAMINE NITRATESCHEMBL148735SCHEMBL2359610SCHEMBL9695641SCHEMBL13560600
이름 더 보기
히드록실아민질산히드록실아민질산(HYDROXYLAMINENITRATE)하이드록실아민 질산염옥스암모늄질산염하이드록실아민질산염하이드록실암모늄질산염히드록실아민질산염HANhydroxyazanium,nitrateHYDROXYLAMMONIUM OXALATEhydroxylamine,nitrate(salt)Hydroxylamine nitrate solutionHydroxylamine solution nitrateHydroxylammonium nitrate solutionHYDROXYLAMINENITRATE,AQUEOUSSOLUTION
Nitric acid--hydroxylamine (1/1)
데이터베이스 식별자
- CAS
13465-08-2- PubChem CID
- 10129901
- DTXSID
DTXSID30884613- EC Number
- 236-691-2
물성
구조 계산 물성
- 극성 표면적
- 112 Ų
- 수소 결합 공여자 수
- 3
- 수소 결합 수용자 수
- 5
- 회전 가능 결합 수
- 0
- 무거운 원자 수
- 6
- 형식 전하
- 0
- 복잡도
- 26.8
실험 및 물리화학적 성질
Chemical ClassesOther Uses -> Explosives
Density1.156 @25 °C
Physical DescriptionAqueous solution; [Sigma-Aldrich MSDS]
물리화학적 성질
- 밀도
- 1.09 g/mL · 1.09 g/mL at 20 °C
- 증기압
- 9.33 hPa · 9.33hPa at 25℃
- 수용성
- 587 g/L · 587g/L at 20℃
- LogP
- -3.6 · -3.6
- EPA
- Hydroxylamine nitrate (13465-08-2)
안전 및 규제
GHS 분류
GHS Classification
Danger
H201: (Deleted) Explosive; mass explosion hazard [Danger Explosives]
P203, P210, P230, P240, P250, P260, P261, P262, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P351+P338, P316, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P370+P380, P372, P373, P391, P401, P405, and P501 (click each P-code to see the statement)
Danger
H201 (100%): (Deleted) Explosive; mass explosion hazard [Danger Explosives]
P203, P210, P230, P240, P250, P260, P261, P262, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P351+P338, P316, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P370+P380, P372, P373, P391, P401, P405, and P501 (click each P-code to see the statement)
유해성 정보
Regulatory InformationStatus: Active Update: 29-04-2013 https://echa.europa.eu/registration-dossier/-/registered-dossier/6670
Hazards Summary
Classifications by the EC: Risk of explosion by shock, friction, fire, or other sources of ignition; Limited evidence of a carcinogenic effect; Toxic in contact with skin; Harmful by ingestion (danger of serious damage to health by prolonged exposure); Irritating to skin and eyes; May cause sensitization by skin contact; [EC: SCCS] A skin and strong eye irritant; May cause CNS depression, respiratory sensitization, and induce methemoglobinemia; Harmful by ingestion; Highly toxic by skin absorption; [Sigma-Aldrich MSDS] See Hydroxylamine. See NITRATES and NITRITES.
Hazard Classes and Categories
Expl. 1.1 (100%)
Explosive - division 1.1
Expl. 1.1 ****
안전 및 보호
Protective Action Criteria (PAC)
0.16 [ppm]
24 [ppm]
92 [ppm]
독성 정보
Treatment
Methemoglobinemia can be treated with supplemental oxygen and methylene blue 1% solution administered intravenously slowly over five minutes followed by IV flush with normal saline. Methylene blue restores the iron in hemoglobin to its normal (reduced) oxygen-carrying state. (L1613)
Health EffectsNitrate and nitrite poisoning causes methemoglobinemia. Nitrites may cause pregnancy complications and developmental effects. They may also be carcinogenic. (L1137)
Adverse EffectsMethemoglobinemia - The presence of increased methemoglobin in the blood; the compound is classified as secondary toxic effect
Exposure RoutesOral (L1137) ; inhalation (L1137)
Toxicity Summary
Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as methemoglobinemia, and is characterized by tissue hypoxia, as methemoglobin cannot bind oxygen. (A2450, L1613)
Signs and Symptoms
Nitrate and nitrite poisoning causes methemoglobinemia. Symptoms include cyanosis, cardiac dysrhythmias and circulatory failure, and progressive central nervous system (CNS) effects. CNS effects can range from mild dizziness and lethargy to coma and convulsions. (L1137)
Carcinogen ClassificationIngested nitrate or nitrite under conditions that result in endogenous nitrosation is probably carcinogenic to humans (Group 2A). (L135)
안전 데이터
- wgk
- 3
- tsca
- TSCA listed
- ridadr
- 1759
- risk_code
- 1-22-36/37/38-43-48/22-34-20/21/22-50
- hazard_code
- Xn,C,Xi,N
- safety_code
- 26-36/37-45-36/37/39-35-61
- 포장분류
- III
- 위험 등급
- 8
- 기존화학 물질
- KE-20606
- 함량 및 규제정보
- 물질구분: 유독물질; 혼합물(제품)함량정보: 히드록실아민과 그 염류 및 그 중 하나를 1% 이상 함유한 혼합물
- 유해화학물질 필터링
- 97-1-411
화학 및 산업
약리 정보
Metabolism/Metabolites
Intake of some amount of nitrates and nitrites is a normal part of the nitrogen cycle in humans. In vivo conversion of nitrates to nitrites can occur in the gastrointestional tract under the right conditions, significantly enhancing nitrates' toxic potency. The major metabolic pathway for nitrate is conversion to nitrite, and then to ammonia. Nitrites, nitrates, and their metabolites are excreted in the urine. (L1137)
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