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기본 정보
- CAS
473722-68-8- 표준 SMILES
CCOc1ccc(-n2c(C(C)N(Cc3cccnc3)C(=O)Cc3ccc(F)c(C(F)(F)F)c3)nc3ncccc3c2=O)cc1- InChIKey
XMRGQUDUVGRCBS-UHFFFAOYSA-N- 분자식
- C32H27F4N5O3
- 평균 분자량
- 605.592 g/mol
- 단동위원소 질량
- 605.2050026
이름 및 식별자
- 우선 이름
- N-{1-[3-(4-Ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl]ethyl}-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-[(pyridin-3-yl)methyl]acetamide
- 영어명
- (±)-NBI 74330
- 분자식
- C32H27F4N5O3
- 분자량
- 605.58
이름 및 동의어
racNBI74330rac NBI 74330(±)-NBI 74330rac-NBI-74330N-[1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamideN-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)benzeneacetamideN-{1-[3-(4-ethoxyphenyl)-4-oxo-3H,4H-pyrido[2,3-d]pyrimidin-2-yl]ethyl}-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-[(pyridin-3-yl)methyl]acetamideBenzeneacetamide, N-[1-[3-(4-ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-2-(4-fluoro-3-trifluoromethyl-phenyl)-N-pyridin-3-ylmethyl-acetamide
데이터베이스 식별자
- CAS
473722-68-8- PubChem CID
- 10167713
- DTXSID
DTXSID901356916- ChEMBL
CHEMBL4173833
물성
물리화학적 성질
- 끓는 점
- 752.5 · 752.5±70.0 °C(Predicted)
- 밀도
- 1.32 · 1.32±0.1 g/cm3(Predicted)
- 용해도
- 50 mM까지 · DMSO에서 50mM까지 용해됨
- 산도 계수 (pKa)
- 4 · 4+-.0.11(Predicted)
화학 및 산업
응용 분야
용도N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benzeneacetamide is a potent and selective CXCR3 antagonist. CXCR3 is a chemokine receptor involved in many inflammatory diseases including rheumatoid arthritis, multiple sclerosis and psoriasis.
공급사15 곳
沈阳中申泽康生物医学技术研究有限公司024-88590548 18698872706 · [email protected]
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United Life Science020-82099279 18988968278 · [email protected]
上海楼岚生物科技有限公司021-52996696，15000506266 15000506266
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
淄博航宇生物科技发展有限公司13053322091 13053322091 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd+86-18341751992 +86-15382112998 · [email protected]
Aladdin Scientific
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