Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
프탈 산
프탈산 · 1,2-벤젠디카복실산 · O-디카르복시벤젠 · O-벤젠디카복실산 · O-프탈 산 · 벤젠-1,2-디카복실산 · 1,2-BENZENEDICARBOXYLIC ACID · BENZENE-1,2-DICARBOXYLIC ACID
식별자 및 물리적 특성
| CAS No. | 88-99-3 |
|---|---|
| 분자식 | C8H6O4 |
| 평균 분자량 | 166.13 g/mol |
| 단동위원소 질량 | 166.02660867 g/mol |
| SMILES | O=C(O)c1ccccc1C(=O)O |
| InChIKey | XNGIFLGASWRNHJ-UHFFFAOYSA-N |
| PubChem CID | 1017 |
| ChEMBL | CHEMBL1045 |
| ChEBI | CHEBI:29069 |
| EC No. | 201-873-2 |
| DTXSID | DTXSID8021484 |
| 현지명 | 프탈 산 |
화학 및 물리적 성질
| XLogP | 0.7 |
|---|---|
| 극성 표면적 | 74.6 |
| 수소 결합 공여자 수 | 2 |
| 수소 결합 수용자 수 | 4 |
| 회전 가능 결합 수 | 2 |
| 무거운 원자 수 | 12 |
| 형식 전하 | 0 |
| 복잡도 | 177 |
| 물질 분류 | Other Classes -> Organic AcidsPhthalate |
| 의약품 | Pharmaceuticals -> Listed in ZINC15 |
| 농약 | Environmental transformation -> Pesticide transformation products (metabolite, successor) |
| LogP(분배 계수) | log Kow = 0.73 |
| 밀도 | 1.593 at 68 °F (NTP, 1992) - Denser than waterwill sink1.593 g/cu cm at 15 °CDensity/specific gravity: 9.4864 kmol/cu m @ 20 °CRelative density (water = 1): 1.62.18 @ 191°C1.59 g/cm3 at 15 °C |
| Color/Form | Colorless crystalsPlates from water |
| 용해도 | less than 1 mg/mL at 68 °F (NTP, 1992)Soluble in alcoholsparingly soluble in ether1 g dissolves in 160 ml water, 10 ml alc, 205 ml ether, 5.3 ml methanolpractically insol in chloroformIn water, 6,965 mg/L at 25 °C7.01 mg/mL at 25 °C메탄올: 0.1 g/mL, 투명 |
| 인화점 | 334 °F (NTP, 1992)334 °F (168 °C) (Closed cup)168 °C c.c. |
| 끓는 점 | Decomposes (NTP, 1992)Boiling point = 598.00 K (Based on predicted value for phthalic acid by Meissner's method with a suitable adjustment for isomerism based on similar compound relationships.)214.32°C (rough estimate) |
| Decomposition | When heated to decomposition it emits acrid smoke and irritating fumes.191 °C |
| 녹는점 | 410 to 412 °F (decomposes) (NTP, 1992)Decomposes at 230 °CMelting point: ca. 210 °C, converted into phthalic anhydride with the elimination of water.Triple point temperature and pressure = 464.15 K (estimated to be equal to the melting point), 7.8183X10+3 PaMelting point = 464.15 K (determined in a sealed tube)210-211 °C (dec.) (lit.) |
| 증기 밀도 | 5.73 (AIR= 1)Relative vapor density (air = 1): 5.7 |
| 증기압 | 7.8 hPa (191 °C) |
| 굴절률 | 1.5100 (estimate) |
| 저장 조건 | Store below +30°C. |
| pKa(산도 계수) | 2.89(at 25℃) |
| 물리적 상태 | 가루 |
| 색상 | 하얀색 |
| pH | 3.2(1 mM solution)2.55(10 mM solution)2(100 mM solution) |
| 용해도 | 7 g/L (25 ºC) |
| 비열 | Cp(crystal): 1.13 J/(g·K), at 25℃ |
| Merck | 14,7371 |
| BRN | 608199 |
| 헨리 상수 | 4.9×105 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) |
| 유전율 | 5.1(Ambient) |
| 안정성 | 안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다. |
| InChI | 1S/C8H6O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)(H,11,12) |
| InChIKey | XNGIFLGASWRNHJ-UHFFFAOYSA-N |
| SMILES | OC(C1=C(C(O)=O)C=CC=C1)=O |
| LogP(분배 계수) | 0.73 at 20℃ |
| NIST | 1,2-Benzenedicarboxylic acid(88-99-3) |
| EPA | Phthalic acid (88-99-3) |
화학적 성질
PHTHALIC ACID,C6H4(COOH)2, mp 208 °C (ortho), 330 °C (meta and iso), the ortho form sublimes and the meta and iso forms decompose with heat, sp gr 1.593 (ortho). Phthalic acid is very slightly soluble in H2O, soluble in alcohol, and slightly soluble in ether. The solid form is colorless, crystalline
안전 및 규제
| GHS 분류 | DangerH360D ***: May damage the unborn child [Danger Reproductive toxicity]P203, P280, P318, P405, and P501 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for 1.1% (3 of 284) of reports.H315 (47.5%): Causes skin irritation [Warning Skin corrosion/irritation] |
|---|---|
| 규제 정보 | Chemical: 1,2-Benzenedicarboxylic acidRegulation (EC) No 1107/2009 (amended)Status: Active Update: 16-12-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/10004Phthalic acid: Does not have an individual approval but may be used under an appropriate group standard |
| 화재 위험 | This chemical is combustible. (NTP, 1992)Combustible. Finely dispersed particles form explosive mixtures in air. |
| 화재 가능성 | Combustible when heated. |
| 건강 유해성 | SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes, mucous membranes, and respiratory passages. In high concentrations, it can cause narcosis. |
| 유해성 요약 | A skin, eye, and respiratory tract irritant[ICSC] Irritating to skin and mucous membranesNo data available on possible toxic effects after ingestion[HSDB] A skin, eye, mucous membrane, and respiratory tract irritantInhalation of high concentrations can cause CNS depression[CAMEO] Causes somnolence and ataxia in lethal-dose feeding studies of mice[RTECS] No evidence of teratogenicity in animal studiesNo human data[REPROTOX] An irritant[MSDSonline] |
| FDA 요건 | o-Phthalic acid is an indirect food additive for use as a component of adhesives. |
| 반응성 그룹 | Acids, Carboxylic |
| Reactivity Profile | PHTHALIC ACID is a carboxylic acid. This chemical is sensitive to exposure to extreme heat. This compound reacts violently with nitric acid. It is incompatible with sodium nitrite. It is also incompatible with oxidizers. (NTP, 1992). |
| Chemical Dangers | The solution in water is a weak acid. |
| Physical Dangers | Dust explosion possible if in powder or granular form, mixed with air. |
| Air and Water Reactions | Insoluble in water. |
| NFPA Hazard Classification | 1 - Materials that, under emergency conditions, can cause significant irritation.1 - Materials that must be preheated before ignition can occur. Materials require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur.0 - Materials that in themselves are normally stable, even under fire conditions. |
| 소화 | Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)Use water spray, powder, alcohol-resistant foam, carbon dioxide. |
| 응급 조치 | Fresh air, rest.Rinse and then wash skin with water and soap.Rinse with plenty of water for several minutes (remove contact lenses if easily possible).Rinse mouth. |
| 응급 처치 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| Firefighting Hazards | Evaporation at 20 °C is negligiblea nuisance-causing concentration of airborne particles can, however, be reached quickly. |
| 소화 절차 | Powder, water spray, foam, carbon dioxide. |
| 정리 방법 | Sweep spilled substance into containersif appropriate, moisten first to prevent dusting (extra personal protection: P1 filter respirator for inert particles). |
| 비화재 누출 대응 | SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. |
| 처리 방법 | SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air qualitypotential migration in soil or watereffects on animal, aquatic, and plant lifeand conformance with environmental and public health regulations. |
| 누출 처리 | Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water. |
| Preventive Measures | Good local & general ventilation are required where phthalic acid is handled.SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants.NO open flames ... Prevent deposition of dustclosed system, dust explosion-proof electrical equipment and lighting ... PREVENT DISPERSION OF DUST ... Do not eat, drink, or smoke during work. |
| Eye Prevention | Wear safety spectacles. |
| Fire Prevention | NO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust. |
| 생태독성 수치 | LC50Species: Bufo bufo japonicus (Toad)Conditions: freshwaterstaticConcentration: 36000 ug/L for 24 hr at 25 °C, pH 5.0 /formulated product/Concentration: >40000 ug/L for 24 hr at 25 °C, pH 6.0 /formulated product/Concentration: >40000 ug/L for 24 hr at 25 °C, pH 7.0 /formulated product/Concentration: >40000 ug/L for 24 hr at 25 °C, pH 8.0 /formulated product/For more Ecotoxicity Values (Complete) data for PHTHALIC ACID (10 total), please visit the HSDB record page. |
| 환경 거동 | TERRESTRIAL FATE: Based on a classification scheme(1), experimental Koc values of 2 to 31(2), indicate that phthalic acid is expected to have very high mobility in soil(SRC). Volatilization of phthalic acid from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 2X10-11 atm-cu derived from its vapor pressure, 6.36X10-7 mm Hg(3), and water solubility, 6965 mg/L(4). Phthalic acid is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(3). Phthalic acid rapidly degraded in Chalmers soil (1.96% organic carbon, pH 6.0)100% decomposition was obtained after 53 days(5).TERRESTRIAL FATE: 14C-Phthalic acid (0.6-600 ppm) was added to the upper 15 cm of Norfolk sandy loam soil in 21 cm high pots and planted with wheat/corn or soybeans/fescue in greenhouse studies(1). The average half-life of phthalic acid (assuming a linear decay) was 37 days for all plantings and application rates. A balance sheet indicated that an average of 5.7% of the originally applied 14C was recovered from soil and plants at the end of the experiment (80 days)most of the phthalic acid was lost through volatilization or decomposition(1). A study was conducted at a plant site where an industrial waste from a terphthalic acid manufacturing facility was injected into the subsurface (259-305 m)(2). While phthalic acid was present at an avg concn of 76 mg/L in the injected waste, phthalic acid was not present in 3 monitoring wells, 2-4 years post injection(2). When phthalic acid was applied at 448,144 kg/ha to field plots in Muskegon City, MI and tilled to 6 inches within 5 days, the 3 plot average in the 0-6 inch layer was 557 ug/kg after 5 days, 424 ug/kg after 122 days and 0 ug/kg after 241 days(3). No phthalic acid was detected in the 9-15 inch core at any of the sampling times(3). No phthalic acid was present in the soil prior to application(3).AQUATIC FATE: Based on a classification scheme(1), experimental Koc values of 2 and 31(2), indicate that phthalic acid is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 2X10-11 atm-cu m/mole(SRC), derived from its vapor pressure, 6.36X10-7 mm Hg(4), and water solubility, 6965 mg/L(5). According to a classification scheme(6), an estimated BCF of 3(SRC), from its log Kow(7) and a regression-derived equation(8), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Phthalic acid completely disappeared from Mississippi River water in 2.5 to 5 wk at concns of 12.5 and 50 mg/L, respectively(9).ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), phthalic acid, which has a vapor pressure of 6.36X10-7 mm Hg at 25 °C(2), will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase phthalic acid is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC)the half-life for this reaction in air is estimated to be 13 days(SRC), calculated from its rate constant of 1.24X10-12 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Particulate-phase phthalic acid may be removed from the air by wet or dry deposition(SRC). Due to its high water solubility and polar nature, phthalic acid is associated with water droplets(4) in the atmosphere and effectively scavenged by rain(5). Experiments suggest that diacids, which mostly exist as particles (aerosols) in the atmosphere, are removed more efficiently during wet precipitation than most water soluble compounds(5). |
| 유해 작용 | Neurotoxin - Other CNS neurotoxin |
| Plant Concentrations | Before the widespread use of phthalate esters, phthalic acid was detected, but not quantified, in raspberries and poppies and the concn in tobacco leaf was 0.02% dry wt(1). |
| Signs and Symptoms | Cough. Sore throat.Redness. |
| Acute Toxicity Link | Chemical: PHTHALIC ACID |
| Effluent Concentrations | In a comprehensive survey of wastewater from 4000 industrial and publicly owned treatment works (POTWs) sponsored by the Effluent Guidelines Division of the U.S. EPA, phthalic acid was identified in discharges of the following industrial categories (positive occurrences, median concn in ppb): leather tanning (38.8), nonferrous metals (55.0), paint and ink (669.8), printing and publishing (1126.2), organics and plastics (5269.5), textile mills (346.1), plastics and synthetics (678.3), auto and other laundries (322.9), pesticides manufacture (22986.4), explosives (1829.5), foundries (711.8), aluminum (37.4), electronics (660.6), organic chemicals (1932.3), mechanical products (211.3), publicly owned treatment works (43.3)(1). The highest effluent concns, and the only ones >1 ppm were 5969 ppb and 4761 ppb in the pesticides manufacture and organics and plastics industries(1). Effluent samples from the Kimberly-Clark Terrace Bay Mill in 1981 contained 0.16 and 0.56 mg/L of phthalic acid(2). Phthalic acid was found in effluent from advanced wastewater treatment plants in Lake Tahoe CA, Orange County CA, Dallas TX, and Washington DC (Blue Plains plant)(3). Phthalic acid was found at concns of 566.9 ug/L of fuel burned from motor vehicle traffic in a Los Angeles roadway tunnel(4). Phthalic acid was found in automobile exhaust: 1982 Toyota Corolla 15 nmol/cu m1971 Mercedes Benz 214 nmol/cu m(5)./detected/ in primary sewage plant effluent: 2 mg/L |
| Soil Adsorption/Mobility | The Koc values were determined for an acidic forest soil (Podzol, 4.85% organic carbon, pH 2.8), an agricultural soil (Alfisol, 1.25% organic carbon, pH 6.7) and a sublimnic soil (sediment from Lake Constance, Germany, 1.58% organic carbon, pH 7.1) as 31, 2 and 2, respectively(1). According to a classification scheme(2), these Koc values suggest that phthalic acid is expected to have very high mobility in soil. Phthalic acid adsorbs strongly to aluminum and iron oxides via a surface ligand exchange reaction(3). Adsorptivity is sensitive to pHfor aluminum oxide the fraction absorbed is >0.8 below pH 6 and falls below 0.1 above pH 7.5(3). |
| Natural Pollution Sources | Phthalic acid in soil may originate from lignin-type organic matter (phenols) which may be converted to aromatic diacids by microbial action(1). Phthalic acid has been found in Russian shale, bacteria, fungus, and Lily of the Valley oil (trace)(2). |
| Atmospheric Concentrations | URBAN/SUBURBAN: The ambient annual average concn of phthalic acid in fine particle organic compounds at four sites on a west to east trajectory, West Los Angeles, downtown Los Angeles, Pasadena, and Rubidouc for 1982 were 60.6, 60.0, 55.7 and 53.5 ng/cu m, respectively(1). 24-Hr samples were collected at 6 day intervals over the year(1). Concns were lowest from Sept to January and highest in February(1). The concn of phthalic acid at a background site on San Nicolas Island, west of Los Angeles, averaged <0.03 ng/cu m from July to December(1). In a study of long-term transport of photochemical air pollution from coastal areas in Japan with large emission sources to inland mountains, the resulting mean concns of phthalic acid in airborne aerosols in a plume at Takasaki (July 26-31, 1986) and Karuizawa (July 29-31, 1986) were 22.1 and 19.5 ng/cu m, respectively(2). Phthalic acid was identified in airborne particulate matter from a suburban area 60 km northeast of Tokyo, Japan in April 1985(3). The concn range of phthalic acid in aerosol samples (n=21) collected from the spring of 1988 to the winter of 1989 in Tokyo, Japan was 4.9-30 ng/cu m(4).URBAN/SUBURBAN: Monitoring of phthalic acid in Los Angeles, CA in 1984: West Los Angeles (n=8) 0.12-1.76 nmol/cu mdowntown (n=2) 1.38-1.95 nmol/cu mgreenhouse (n=2) 0.15-0.55 nmol/cu m(1). Atmospheric concns of phthalic acid were measured in the southeastern United States from April 1999 to January 2000North Birmingham, Al 5.88 ng/cu m, Jefferson Street, Atlanta, GA 5.98 ng/cu m, Gulfport, MS 2.32 ng/cu m, Pensacola, FL 2.87 ng/cu m and OLF#8, FL 2.07 ng/cu m(3). Tokyo aerosol concns: Feb 1992 (n=2): 130 ng/cu m, 85 ng/cu mJuly 1992: (n=2) 135 ng/cu m, 157 ng/cu m(2). Phthalic acid was the third most abundant diacid in Tokyo, Japan aerosols(2). A study of water-soluble organic compounds in urban atmospheric particles from Kobe City, Japan found that phthalic acid was detected in the 0.43-1.1 um size fraction with concentrations of <2.80 ng/cu m from Aug 3-14, 1998, 3.03 ng/cu m from Oct 7-19, 1998, 4.20 ng/cu m from Mar 1-26, 1999 and 3.64 ng/cu m from Apr 27- May 17, 1999(4).URBAN/SUBURBAN: Wintertime atmospheric concentrations of phthalic acid were measured in Fresno, CA as 9.16 ng/cu m for the sampling period Dec 26-28, 1995 and 9.09 ng/cu m for the sampling period of Jan 4-6, 1996(1). Wintertime concentrations were also measured in Bakersfield, CA as 6.78 ng/cu m for the sampling period Dec 26-28, 1995 and 13.1 ng/cu m for the sampling period of Jan 4-6, 1996(9). Five urban sites were analyzed for phthalic acid in southern California in 1995Long Beach 3.51 ng/cu m, Mira Loma 3.19 ng/cu m, Riverside 4.51 ng/cu m, San Dimas 4.54 ng/cu m and Upland 4.07 ng/cu m(2). Continental background aerosol levels of phthalic acid were measured in Tokyo, Japan, Vienna, Austria and Los Angeles, CA at 135 ng/cu m, 18 ng/cu m and 60 ng/cu m, respectively(3). Samples taken from four sites in the Los Angeles, CA area September 8-9, 1993 found an average of 80.2 ng/cu m of phthalic acid in atmospheric fine particulates(4).INDOOR AIR: Phthalic acid was identified in particulate matter in air in Chinese homes burning smokeless coal(1).RURAL/REMOTE: Atmospheric concentrations of phthalic acid were measured in the southeastern United States from April 1999 to January 2000Centreville, AL 5.94 ng/cu m, Yorkville, GA 3.59 ng/cu m and Oak Grove, MS 2.54 ng/cu m(1). Wintertime atmospheric concentrations of phthalic acid were measured in Kern Wildlife Refuge, CA as 4.71 ng/cu m for the sampling period Dec 26-28, 1995 and 5.43 ng/cu m for the sampling period of Jan 4-6, 1996(2). Four rural sites were analyzed for phthalic acid in southern California in 1995Atascadere 4.13 ng/cu m, Lake Elsinore 3.01 ng/cu m, Lompoc 1.39 ng/cu m and Santa Maria 1.97 ng/cu m(3). Two mountain sites and one desert site were also analyzedAlpine 4.6 ng/cu m, Lake Arrowhead 8.17 ng/cu m and Lancaster 2.99 ng/cu m(3). Continental background aerosol levels of phthalic acid were measured in South Africa, Salzburg, Austria and Antarctica at 3.3 ng/cu m, 3.3 ng/cu m and 1.7 ng/cu m, respectively(4). Concentrations of phthalic acid were measured in arctic aerosols from July of 1987 to June of 1988 ranging from <0.005 ng/cu m to 5.8 ng/cu m(5). |
| Human Toxicity Excerpts | /SIGNS AND SYMPTOMS/ There have been reports of conjunctivitis, bloody nasal excreta, atrophy of nasal mucosa, hoarseness, cough and bronchitis in workers employed on the production of phthalic acid and anhydride./SIGNS AND SYMPTOMS/ ACUTE ... SYMPTOMS: Inhalation--cough, sore throat. Skin--redness. Eyes--redness, pain./CASE REPORTS/ ... A factory worker has been in contact with raw tributyl tin phthalate on one leg. Soon after taking a hot-water bath, he developed severely painful erythema on this leg. Patch tests and chemical analysis revealed that hot water hydrolyzed tributyl tin phthalate and produced concentrated phthalic acid./EPIDEMIOLOGY STUDIES/ A large population based case control study evaluated occupational exposures in 1,098 Danish males diagnosed with multiple myeloma from 1970 to 1984 and in 4,169 age and gender matched controls alive at the time of case diagnosis. Associations with phthalates persisted, but were inconsistent with duration and probability of exposure. /Phthalates//OTHER TOXICITY INFORMATION/ The rapid proliferation of complex plastic polymers and resins has led to a marked incr of work induced asthma due to low molecular weight agents. Phthalates are frequently used in the manufacture of epoxy resins, plasticizers, adhesives and a wide variety of other materials. They have recently been identified as an important irritant and immunogen of at least four occupational respiratory syndromes, ie, asthma/rhinitis, late respiratory systemic syndrome,pulmonary disease-anemia syndrome, and an irritant reaction. /Phthalates/ |
| Fish/Seafood Concentrations | Composite biota samples from Lake Ponchartrain (New Orleans, LA) a shallow estuary in the Mississippi delta: Chef Menteur clams 630 ppbRigolete clams 330 ppb(1). Jellyfish (N. Atlantic) 0.01% wet wt(2). |
| 수질 위해 등급(WGK) | 1 |
| TSCA 등재 상태 | TSCA listed |
| RTECS 번호 | TH9625000 |
| 독성 | LD50 orally in rats: 7.9 g/kg (Shaffer) |
| 관세 코드 | 29173980 |
| 위험 문구(R) | 36/37/38 |
| 위험 표시 | Xi |
| 안전 문구(S) | 26-36-37/39 |
| 기존화학 물질 | KE-02188 |
| 위험 등급 | Eye Dam. 1 |
| 저장 분류 | 11 - Combustible Solids |
| 유해 물질 데이터 | 88-99-3(Hazardous Substances Data) |
용도
용도
에폭시수지,경화제.
개요
Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2. It is an isomer of isophthalic acid and terephthalic acid. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale.
용도
It is a dibasic acid, with pKa's of 2.89 and 5.51. The mono potassium salt, potassium hydrogen phthalate is a standard acid in analytical chemistry. Typically phthalate esters are prepared from the widely available phthalic anhydride. Reduction of phthalic acid with sodium amalgam in the presence of water gives the 1,3- cyclohexadiene derivative.
일반 설명
White crystals or fine white powder.
제조 및 합성 방법
생산 방법
Phthalic acid is produced by the catalytic oxidation of naphthalene directly to phthalic anhydride and a subsequent hydrolysis of the anhydride. Phthalic acid was first obtained by French chemist Auguste Laurent in 1836 by oxidizing naphthalene tetrachloride. Believing the resulting substance to be a naphthalene derivative, he named it "naphthalic acid". After the Swiss chemist Jean Charles Galissard de Marignac determined its correct formula, Laurent gave it its present name. Manufacturing methods in the nineteenth century included oxidation of naphthalene tetrachloride with nitric acid, or, better, oxidation of the hydrocarbon with fuming sulfuric acid, using mercury or mercury(II) sulfate as a catalyst.