기본 정보
- CAS
175357-18-3- 표준 SMILES
C=CCCCCCCCCC(=O)N[C@@H](Cc1ccccc1)C(=O)O- InChIKey
RTBWWWVNZWFNBV-SFHVURJKSA-N- 분자식
- C20H29NO3
- 평균 분자량
- 331.4 g/mol
- 단동위원소 질량
- 331.21474379
개요
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Undecylenoyl Phenylalanine...
이름 및 식별자
- 우선 이름
- Sepiwhite
- IUPAC
- (2S)-3-phenyl-2-(undec-10-enoylamino)propanoic acid
- 현지명
- 운데실레노일페닐알라닌
- 영어명
- Undecylenoyl phenylalanine
- 분자식
- C20H29NO3
- 분자량
- 331.45
이름 및 동의어
undecylenoyl phenylalanine175357-18-3SepiwhiteSepiwhite mshundecylenoylphenylalanineSepiwhite msh QDN-Undecenoyl-L-phenylalanineL-Phenylalanine, N-(1-oxo-10-undecenyl)-L-Phenylalanine, N-(1-oxo-10-undecen-1-yl)-271P08C6ODDTXSID701018253RefChem:901093
이름 더 보기
운데실레노일페닐알라닌LGB UPSkinWhite MSHSepiwhite MSH powderWhiteningingredientα-MSHUndecarbonyl phenylalanine11-CarbonenoylphenylalanineUndecylenoyl Phenylalanine/MSHUNDECYLENOYL PHENYLALANINE USP/EP/BP
DTXCID801476490(2S)-3-phenyl-2-(undec-10-enoylamino)propanoic Acid(S)-3-Phenyl-2-(undec-10-enamido)propanoic acidUNII-271P08C6ODUndecylenoyl phenylalanine [INCI](2S)-3-phenyl-2-[[(E)-undec-2-enoyl]amino]propanoic AcidUNDECYLENOYL PHENYLALANINE (SEPIWHITE)N-(1-oxo-10-undecen-1-yl)-L-Phenylalanine
데이터베이스 식별자
- CAS
175357-18-3
물성
구조 계산 물성
- XLogP
- 5.2
- 극성 표면적
- 66.4 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 3
- 회전 가능 결합 수
- 13
- 무거운 원자 수
- 24
- 형식 전하
- 0
- 복잡도
- 375
실험 및 물리화학적 성질
CosmeticsCosmetic ingredients (Undecylenoyl Phenylalanine) -> CIR (Cosmetic Ingredient Review)
물리화학적 성질
- 녹는점
- 109 · 109-112 °C
- 끓는 점
- 540 · 540.0±50.0 °C(Predicted)
- 밀도
- 1.047 · 1.047±0.06 g/cm3(Predicted)
- 증기압
- 0 · 0-0Pa at 25-60℃
- 용해도
- 10 mg/mlEthanol: · DMSO: Soluble: =10 mg/mlEthanol: Sparingly soluble: 1-10 mg/ml
- 산도 계수 (pKa)
- 3.63 · 3.63±0.10(Predicted)
- 화장품 원료 기능
- 피부 컨디셔닝
- InChI
- InChI=1S/C20H29NO3/c1-2-3-4-5-6-7-8-12-15-19(22)21-18(20(23)24)16-17-13-10-9-11-14-17/h2,9-11,13-14,18H,1,3-8,12,15-16H2,(H,21,22)(H,23,24)/t18-/m0/s1
- InChIKey
- RTBWWWVNZWFNBV-SFHVURJKSA-N
- SMILES
- C(O)(=O)[C@H](CC1=CC=CC=C1)NC(=O)CCCCCCCCC=C
- LogP
- -0.04 · -0.04-3.3 at pH2-7
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 38 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
유해성 정보
Regulatory InformationStatus: Active Update: 22-10-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/23617
Hazard Classes and Categories
Eye Dam. 1 (100%)
Skin Irrit. 2 (100%)
독성 정보
Toxicity Summary
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Undecylenoyl Phenylalanine...
Safe for use in cosmetics, with qualifications
안전 데이터
- 신호 어
- Warning
- 유해·위험 문구
- 암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H302
화학 및 산업
용도 및 제조
UsesCIR ingredient: Undecylenoyl Phenylalanine
Household ProductsInformation on 2 consumer products that contain Undecylenoyl Phenylalanine in the following categories is provided:
응용 분야
개요Undecylenoyl Phenylalanine is a chemical compound—a substituted amino acid derivative—that is used in skin conditioning agents in different brands of whitening creams and other skin care topical products. The compound helps regulate skin pigmentation, thereby, improving skin tone and its fairness.Undecylenoyl phenylalanine is a possible antagonist of alpha-melanocyte-stimulatinghormone. It inhibits melanotropin, a melanin stimulator found in the skin. Melanotropin controls tyrosinase activity (tyrosinase being an essential enzyme in the production of melanin), melanin (eumalanin) synthesis and melanosome; therefore, by preventing the production of melanotropin, the pigmentation process is reduced or halted.
용도Undecylenoyl phenylalanine is a novel skin-lightening agent, probably acting as α-melanocyte-stimulating hormone (α-MSH) and beta-adrenergic receptor (β-ADR) antagonist.
공급사100 곳
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
杭州林格贝科技有限公司17857936637 · [email protected]
湖北威德利化学试剂有限公司186-02735115 18062128043 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
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