트리메틸아민 하이드로클로라이드

Trimethylamine Hydrochloride

HCID 10313079

기본 정보

CAS
593-81-7
표준 SMILES
CN(C)C.Cl
InChIKey
SZYJELPVAFJOGJ-UHFFFAOYSA-N
분자식
C3H9N.ClH
평균 분자량
95.57 g/mol
단동위원소 질량
95.050177

개요

Trimethylamine hydrochloride is a hydrochloride salt formed by reaction of equimolar amounts of trimethylamine and hydrogen chloride. It contains a trimethylammonium.

이름 및 식별자

우선 이름
Trimethylamine Hydrochloride
IUPAC
N,N-dimethylmethanamine;hydrochloride
현지명
트리메틸아민 하이드로클로라이드
영어명
Trimethylamine hydrochloride
분자식
C3H10ClN
분자량
95.57

이름 및 동의어

Trimethylamine hydrochloride593-81-7TRIMETHYLAMMONIUM CHLORIDEHEGZADESILN,N-dimethylmethanamine;hydrochlorideDTXSID5027229N,N-dimethylmethanamine hydrochlorideMe3N.HClNSC-91484(CH3)3N.HClDTXCID307229CHEBI:64700
이름 더 보기
트리메틸아민수화염화물트리메틸아민하이드로클로라이드트리메틸아민수화염화물트라이메틸암모늄 클로라이드메탄아민, N,N-다이메틸-, 하이드로클로라이드염화 트라이메틸암모늄트라이메틸아민 하이드로클로라이드TRIMETHYLAMINE HCLFEMA 3241Trimthylamine bydrochlorideN, N-DIMETHYLMETHYLAMINE HCLTrimethylamine monohydrochlorideTrimethylammonium monohydrochlorideMethanamine,N,N-dimethyl-,hydrochlorideHJ 1042-2019)TrimethylamineHcl99%
N,N-dimethylmethanaminium chlorideUNII-UW38SRM77KTRIMETHYLAMINE HYDROCHLORIC ACIDHSDB 5710TRIMETHYLAMINE HYDROCHLORIDE [MI]TRIMETHYLAMMONIUM CHLORIDE [HSDB]EINECS 209-810-0NSC 91484

데이터베이스 식별자

CAS
593-81-7
PubChem CID
10313079
DTXSID
DTXSID5027229
ChEMBL
CHEMBL450057
ChEBI
CHEBI:64700
UNII
UW38SRM77K
EC Number
209-810-0

물성

구조 계산 물성

극성 표면적
3.2 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
1
회전 가능 결합 수
0
무거운 원자 수
5

실험 및 물리화학적 성질

Chemical ClassesNitrogen Compounds -> Amines, Aliphatic
Pesticides · 2건

Agrochemicals -> Pesticide active substances

Active substance -> EU Pesticides database: Not approved

OdorODOR LESS INTENSE THAN THAT OF BASE
Color/FormMONOCLINIC CRYSTALS FROM ALCOHOL
SolubilitySol in water, ethanol, and chloroform
Boiling PointSub 200 °C

물리화학적 성질

녹는점
283 · 283-284 °C (dec.)(lit.)
끓는 점
132.32 °C · 132.32°C (rough estimate)
밀도
0.9337 · 0.9337 (rough estimate)
증기압
0 Pa · 0Pa at 25℃
굴절률
1.4413 · 1.4413 (estimate)
저장 조건
30 °C · Store below +30°C.

화학적 성질

white to slightly cream crystalline powder

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 16.6% (42 of 253) of reports.

Warning

H315 (83.4%): Causes skin irritation [Warning Skin corrosion/irritation]

P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)

Aggregated GHS information provided per 253 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

유해성 정보

Regulatory Information · 5건

Chemical: Methanamine, N,N-dimethyl-, hydrochloride

Commission Regulation (EC) No 2229/2004

2008/127, Reg. (EU) 2022/801, Reg. (EU) No 540/2011

Status: Active Update: 19-12-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/14311

Trimethylammonium chloride: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryAn irritant; May be harmful by ingestion, inhalation, or skin absorption; [Aldrich MSDS]
Hazard Classes and Categories · 2건

Skin Irrit. 2 (83.4%)

Acute toxicity (inhalation) - category 4

안전 및 보호

Storage ConditionsKEEP WELL CLOSED.
Disposal Methods · 1건

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

안전 데이터

wgk
1
tsca
TSCA listed
rtecs
YH2700000
독성
LD50 orally in Rabbit: 3090 mg/kg
HS 번호
29211190
risk_code
36/37/38-38-36

화학 및 산업

약리 정보

Metabolism/MetabolitesRESULTS OF EXPERIMENTS WITH TRIMETHYLAMINE-HCL SUGGESTED THAT TRIMETHYLAMINE IS AN INTERMEDIATE IN THE CONVERSION OF CHOLINE TO DIMETHYLAMINE.

용도 및 제조

Uses · 3건

Used as an insect attractant and to make quaternary ammonium compounds; [HSDB] Formed in the stomach from ingestion of trimethylamine which is found naturally in foods; [IUCLID]

IN MANUFACTURE OF QUATERNARY AMMONIUM COMPOUNDS; AS INSECT ATTRACTANT;

CAPTIVE CHEM INT

U.S. Production(1977) AT LEAST 5.45X10+9 G (CAPTIVE PRODN)
Methods of ManufacturingREACTION OF TRIMETHYLAMINE & HYDROCHLORIC ACID
General Manufacturing InformationMethanamine, N,N-dimethyl-, hydrochloride (1:1): ACTIVE
응용 분야 · 1건

용도Trimethylamine hydrochloride is used in the manufacture of quaternary ammonium compounds, as insect attractant. It is also used as a raw material for the synthesis of choline chloride and ion exchange resins. Additionally, It acts as a cationic starch reagent, phase transfer catalyst, oil field chemicals, warning agent for natural gas and flotation agent.

제조 방법 · 1건

Trimethylamine hydrochloride can be synthesized through the reaction of trimethylamine (TMA) and hydrochloric acid (HCl). The synthesis reaction can be written as follows:C3H9N+ HCl → C3H10ClNThe following steps are involved in obtaining trimethylamine hydrochloride:Step 1: Evaporation of hydrochloric acid solution The hydrochloric acid solution is evaporated, first over a free flame, and later on a steam bath. This process results in concentration of the solution, which aids in the formation of trimethylamine hydrochloride crystals.Step 2: Crystal formation and filtration As the solution becomes more and more concentrated, the trimethylamine hydrochloride crystals begin to form. The crystals are filtered periodically to remove them from the solution.Step 3: Drying The filtered crystals are dried in an air bath for a few minutes, with a temperature range of 100-110°.Step 4: Storage The air-dried crystals are then stored in a tightly closed bottle.Step 5: Centrifugation (optional) If the trimethylamine hydrochloride crystals are centrifuged, the product is obtained pure and dry.Overall, four runs yield an average of 710 g of pure trimethylamine hydrochloride and 82 g of slightly yellow-tinted product. This yield is equivalent to 89% of the theoretical amount based on ammonium chloride. The slight yellow coloration results from the evaporation of the last traces of solution.DOI: 10.15227/orgsyn.001.0079

공급사102 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
爱斯特(成都)生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

추가 설명

정의ChEBI: Trimethylamine hydrochloride is a hydrochloride salt formed by reaction of equimolar amounts of trimethylamine and hydrogen chloride. It contains a trimethylammonium.

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