CAS 118026-14-5 2-hydroxy-N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide (HCID 10336316)

기본 정보

CAS: 118026-14-5
표준 SMILES: Cc1ccc(-c2nc3ccc(C)cn3c2C(O)C(=O)N(C)C)cc1
InChIKey: XSPMDGULXBYBFC-UHFFFAOYSA-N
분자식: C19H21N3O2
평균 분자량: 323.4 g/mol

이름 및 식별자

우선 이름: 2-hydroxy-N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide
IUPAC: 2-hydroxy-N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide
영어명: 6-Methyl-N,N-dimethyl-2-(4-methylphenyl)-2-hydroxyimidazo[1,2-alpha]pyridine-3-acetamide
분자식: C19H21N3O2
분자량: 323.39

이름 및 동의어

2-hydroxy-N,N-dimethyl-2-(6-methyl-2-(4-methylphenyl)imidazo(1,2-a)pyridin-3-yl)acetamide2-hydroxy-N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamideRefChem:473346601-503-3alpha-Hydroxy ZolpidemSCHEMBL436359XSPMDGULXBYBFC-UHFFFAOYSA-N6-methyl-N,N-dimethyl-2-(4-methylphenyl)-alpha-hydroxyimidazo [1,2-a]pyridine-3-acetamide6-methyl-n,n-dimethyl-2-(4-methylphenyl)-alpha-hydroxyimidazo[1,2-a]pyridine-3-acetamideα-HydroxyzolpidemZolpidem Impurity 13Zolpidem tartrate Impurity 17

이름 더 보기

IMidazo[1,2-a]pyridine-3-acetaMide, a-hydroxy-N,N,6-triMethyl-2-(4-Methylphenyl)-Imidazo[1,2-a]pyridine-3-acetamide, α-hydroxy-N,N,6-trimethyl-2-(4-methylphenyl)-6-METHYL-N,N-DIMETHYL-2-(4-METHYLPHENYL)-2-HYDROXYIMIDAZO[1,2-A]PYRIDINE-3-ACETAMIDE6-Methyl-N,N-dimethyl-2-(4-methylphenyl)-2-hydroxyimidazo[1,2-alpha]pyridine-3-acetamide2-(2-Hydroxy-6-methyl-2-(p-tolyl)-2,3-dihydroimidazo[1,2-a]pyridin-3-yl)-N,N-dimethylacetamide

물성

구조 계산 물성

XLogP: 1.9
극성 표면적: 57.8 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 3
회전 가능 결합 수: 3
무거운 원자 수: 24
형식 전하: 0
복잡도: 448

실험 및 물리화학적 성질

DrugsPharmaceuticals -> Metabolite of Zolpidem

물리화학적 성질

녹는점: 175 · 175-177 °C
밀도: 1.19 · 1.19±0.1 g/cm3(Predicted)
산도 계수 (pKa): 12.04 · 12.04±0.20(Predicted)

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 3 reports by companies from 1 notifications to the ECHA C&L Inventory.

유해성 정보

Regulatory InformationStatus: Active Update: 30-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/17953

Hazard Classes and CategoriesAcute Tox. 4 (100%)

안전 데이터

신호 어: Warning
유해·위험 문구: 암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H302

화학 및 산업

응용 분야

용도α-Hydroxyzolpidem is a impurity of Zolpidem (Z650000), a selective non-benzodiazepine GABAA receptor agonist. Sedative, hypnotic. Controlled substance (depressant).

상·하류 제품 정보

상류 원료

졸피뎀

공급사19 곳

济南百隆化学有限公司[email protected] · [email protected]

广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]

北京科迈启医药科技有限公司15910349257 15910349257 · [email protected]

广州隽唐科技有限公司020-36607679 13502246435 · [email protected]

希瓦生物科技（广州）有限公司13268215580 · [email protected]

화합물 노트

불러오는 중…

2-hydroxy-N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide