7519-36-0O=NN1CCC[C@H]1C(=O)OWLKPHJWEIIAIFW-BYPYZUCNSA-N7519-36-0DTXSID3021061CHEMBL4566042CHEBI:82515Colourless Plates
This chemical does not meet GHS hazard criteria for 66.7% (4 of 6) of all reports.
Danger
H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral];H312 (33.3%): Harmful in contact with skin [Warning Acute toxicity, dermal];H315 (33.3%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (33.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H332 (33.3%): Harmful if inhaled [Warning Acute toxicity, inhalation];H334 (33.3%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory];H335 (16.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H341 (33.3%): Suspected of causing genetic defects [Warning Germ cell mutagenicity];H351 (33.3%): Suspected of causing cancer [Warning Carcinogenicity]
P203, P233, P260, P261, P264, P264+P265, P270, P271, P280, P284, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 6 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 4 of 6 reports by companies.;There are 2 notifications provided by 2 of 6 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
용도A nitrosoamino acid with oncogenicity. The LD50 of a single ip dose given to Swiss-Webster mice is 203 +/- 22 mg / kg
생산 방법There is no indication that nitrosoproline was made commercially. It has been reported in cured meats (e.g., bacon) at concentrations of 340–440 μg/kg. Both higher and lower levels in several cured products have been reported by several authors.
불러오는 중…
N-Nitrosoproline
Group 3: Not classifiable as to its carcinogenicity to humans
Volume 17: (1978) Some N-Nitroso Compounds;Volume Sup 7: Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, 1987; 440 pages; ISBN 92-832-1411-0 (out of print)
1987
1987