Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용

HCID 10431생성일: 2026년 10월 27일

카코딜록사이드

카코딜록사이드 · TL-297 · Oxybis(dimethylarsine) · Bis(dimethylarsine) oxide · Bis(dimethylarsinous)anhydride · Arsinous acid, As,As-dimethyl-, anhydride

https://huagongshe.com/ko/chemical/10431

식별자 및 물리적 특성

CAS No.	503-80-0
분자식	C4H12As2O
평균 분자량	225.98 g/mol
단동위원소 질량	225.932 g/mol
SMILES	C[As](C)O[As](C)C
InChIKey	LOKPKYSOCCPWIZ-UHFFFAOYSA-N
PubChem CID	10431
DTXSID	DTXSID70198307
현지명	카코딜록사이드

화학 및 물리적 성질

극성 표면적	9.2
수소 결합 공여자 수	0
수소 결합 수용자 수	1
회전 가능 결합 수	2
무거운 원자 수	7
형식 전하	0
복잡도	39
녹는점	-25°C
끓는 점	150°C
밀도	1.482
굴절률	1.5225
물리적 상태	액체

안전 및 규제

Minimum Risk Level	Acute Oral: 0.005 mg/kg/day (L134) Chronic Oral: 0.0003 mg/kg/day (L134) Chronic Inhalation: 0.01 mg/m3 (L134)
Treatment	Arsenic poisoning can be treated by chelation therapy, using chelating agents such as dimercaprol, EDTA or DMSA. Charcoal tablets may also be used for less severe cases. In addition, maintaining a diet high in sulfur helps eliminate arsenic from the body. (L20)
건강 영향	Arsenic poisoning can lead to death from multi-system organ failure, probably from necrotic cell death, not apoptosis. Arsenic is also a known carcinogen, esepcially in skin, liver, bladder and lung cancers. (T1, L20)
노출 경로	Oral (L2)inhalation (L2)dermal (L2)
독성 요약	Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis. Hydrogen peroxide production is also increased, which might form reactive oxygen species and oxidative stress. Arsenic's carginogenicity is influenced by the arsenical binding of tubulin, which results in aneuploidy, polyploidy and mitotic arrests. The binding of other arsenic protein targets may also cause altered DNA repair enzyme activity, altered DNA methylation patterns and cell proliferation. (T1, A17)
Signs and Symptoms	Exposure to lower levels of arsenic can cause nausea and vomiting, decreased production of red and white blood cells, abnormal heart rhythm, damage to blood vessels, and a sensation of
Carcinogen Classification	3, not classifiable as to its carcinogenicity to humans. (L135)

CAS No.

503-80-0

분자식

C4H12As2O

평균 분자량

225.98 g/mol

단동위원소 질량

225.932 g/mol

SMILES

C[As](C)O[As](C)C

InChIKey

LOKPKYSOCCPWIZ-UHFFFAOYSA-N

PubChem CID

10431

DTXSID

DTXSID70198307

현지명

카코딜록사이드

극성 표면적

9.2

수소 결합 공여자 수

수소 결합 수용자 수

회전 가능 결합 수

무거운 원자 수

형식 전하

복잡도

녹는점

-25°C

끓는 점

150°C

밀도

1.482

굴절률

1.5225

물리적 상태

액체

안전 및 규제

Minimum Risk Level

Acute Oral: 0.005 mg/kg/day (L134) Chronic Oral: 0.0003 mg/kg/day (L134) Chronic Inhalation: 0.01 mg/m3 (L134)

Treatment

Arsenic poisoning can be treated by chelation therapy, using chelating agents such as dimercaprol, EDTA or DMSA. Charcoal tablets may also be used for less severe cases. In addition, maintaining a diet high in sulfur helps eliminate arsenic from the body. (L20)

건강 영향

Arsenic poisoning can lead to death from multi-system organ failure, probably from necrotic cell death, not apoptosis. Arsenic is also a known carcinogen, esepcially in skin, liver, bladder and lung cancers. (T1, L20)

노출 경로

Oral (L2)inhalation (L2)dermal (L2)

독성 요약

Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis. Hydrogen peroxide production is also increased, which might form reactive oxygen species and oxidative stress. Arsenic's carginogenicity is influenced by the arsenical binding of tubulin, which results in aneuploidy, polyploidy and mitotic arrests. The binding of other arsenic protein targets may also cause altered DNA repair enzyme activity, altered DNA methylation patterns and cell proliferation. (T1, A17)

Signs and Symptoms

Exposure to lower levels of arsenic can cause nausea and vomiting, decreased production of red and white blood cells, abnormal heart rhythm, damage to blood vessels, and a sensation of

Carcinogen Classification

3, not classifiable as to its carcinogenicity to humans. (L135)