SYBR(R)녹색I핵산젤얼룩
SYBR Green I
기본 정보
- CAS
163795-75-3- 표준 SMILES
CCCN(CCCN(C)C)c1cc(/C=C2/Sc3ccccc3N2C)c2ccccc2[n+]1-c1ccccc1- InChIKey
CGNLCCVKSWNSDG-UHFFFAOYSA-N- 분자식
- C32H37N4S+
- 평균 분자량
- 509.7 g/mol
- 단동위원소 질량
- 509.27389337
개요
binds to double stranded DNA of less than 20 pg following agarose or polyacrylamide gel electrophoresis; excited at 497 nm and emits at 520 nm
이름 및 식별자
- 우선 이름
- SYBR Green I
- IUPAC
- N,N-dimethyl-N'-[4-[(E)-(3-methyl-1,3-benzothiazol-2-ylidene)methyl]-1-phenylquinolin-1-ium-2-yl]-N'-propylpropane-1,3-diamine
- 현지명
- SYBR(R)녹색I핵산젤얼룩
- 영어명
- SYBR(R) green I nucleic acid gel stain
- 분자식
- C32H37N4S
- 분자량
- 0
이름 및 동의어
Sybr green I163795-75-3CHEBI:51461DTXSID60936871sybr greenRefChem:890090DTXCID70997958SYBR(R) GREEN I NUCLEIC ACID GEL STAINN,N-dimethyl-N'-[4-[(E)-(3-methyl-1,3-benzothiazol-2-ylidene)methyl]-1-phenylquinolin-1-ium-2-yl]-N'-propylpropane-1,3-diamine178918-96-22-[[3-(Dimethylamino)propyl]propylamino]-4-[(3-methyl-2(3H)-benzothiazolylidene)methyl]-1-phenylquinoliniumSCHEMBL2556511
이름 더 보기
SYBR(R)녹색I핵산젤얼룩SYBR? gSYBGREENSybrgreenCcris 8512eic acid gSYBRGREENⅠreen I nucLSYBR Green 1eic acid geL
SCHEMBL29480842SCHEMBL31151035(E)-2-((2-((3-(dimethylamino)propyl)(propyl)amino)-1-phenylquinolin-4(1H)-ylidene)methyl)-3-methylbenzo[d]thiazol-3-ium2-[N-(3-dimethylaminopropyl)-N-propylamino]-4-[2,3-dihydro-3-methyl-(benzo-1,3-thiazol-2-yl)-methylidene]-1-phenyl-quinolinium2-{(E)-[2-{[3-(dimethylamino)propyl](propyl)amino}-1-phenylquinolin-4(1H)-ylidene]methyl}-3-methyl-1,3-benzothiazol-3-ium2-{[3-(dimethylamino)propyl](propyl)amino}-4-[(E)-(3-methyl-1,3-benzothiazol-2(3H)-ylidene)methyl]-1-phenylquinoliniumEX-A5406Thiazole Green (SYBR Green I), 10,000X in DMSO
데이터베이스 식별자
- CAS
163795-75-3、178918-96-2- PubChem CID
- 10436340
- EC Number
- 838-836-0
물성
구조 계산 물성
- XLogP
- 8.2
- 극성 표면적
- 38.9 Ų
- 수소 결합 공여자 수
- 0
- 수소 결합 수용자 수
- 4
- 회전 가능 결합 수
- 9
- 무거운 원자 수
- 37
- 형식 전하
- 1
- 복잡도
- 734
물리화학적 성질
- 인화점
- 94 ℃ · 94℃
- 저장 조건
- -20 °C · -20°C
- 용해도
- good in DMSO
- 물리적 상태
- solution
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports.
Warning
H341 (50%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory.
유해성 정보
Hazard Classes and CategoriesMuta. 2 (50%)
안전 데이터
- wgk
- 1
- F 고인화성물질
- 3
- 스토리지 클래스
- 10 - Combustible liquids
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.
응용 분야
용도SYBR Green I nucleic acid gel stain has been used for real-time PCR quantification and flow cytometry.
일반 설명SYBR Green I is an asymmetrical cyanine dye, which is used to detect nucleic acids. It consists of a N-alkylated benzothiazolium or benzoxazolium ring system, that is joined by a monomethine bridge to a pyridinium or quinolinium ring system. SYBR Green I binds to the minor groove of dsDNA and is excited at a wavelength of 480 nm. It has a peak fluorescence emission of 520 nm.
추가 설명
정의ChEBI: SYBR Green I is a cationic unsymmetrical cyanine dye used as a nucleic acid stain in molecular biology. SYBR Green I binds to double-stranded DNA.
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