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HCID 10460생성일: 2026년 10월 27일

Hexenal

https://huagongshe.com/ko/chemical/10460

식별자 및 물리적 특성

CAS No.	1335-39-3
분자식	C6H10O
평균 분자량	98.14 g/mol
단동위원소 질량	98.07316494 g/mol
SMILES	CCCC=CC=O
InChIKey	MBDOYVRWFFCFHM-UHFFFAOYSA-N
PubChem CID	10460
DTXSID	DTXSID7021609

화학 및 물리적 성질

XLogP	1.5
극성 표면적	17.1
수소 결합 공여자 수	0
수소 결합 수용자 수	1
회전 가능 결합 수	3
무거운 원자 수	7
형식 전하	0
복잡도	64.6
SpringerMaterials Properties	Dielectric constant
EPA	Hexenal (1335-39-3)

안전 및 규제

규제 정보	Chemical: Hexenal
기타 안전 정보	Evaluation - Chemicals not considered for in depth evaluation - Not commercially active in Australia
Treatment	Kidney dialysis is usually needed to relieve the symptoms of uremic syndrome until normal kidney function can be restored.
건강 영향	Chronic exposure to uremic toxins can lead to a number of conditions including renal damage, chronic kidney disease and cardiovascular disease.
노출 경로	Endogenous, Ingestion, Dermal (contact)
독성 요약	Uremic toxins such as 2-Hexenal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulate the production of reactive oxygen species. This seems to be mediated by the direct binding or inhibition by uremic toxins of the enzyme NADPH oxidase (especially NOX4 which is abundant in the kidneys and heart) (A7868). Reactive oxygen species can induce several different DNA methyltransferases (DNMTs) which are involved in the silencing of a protein known as KLOTHO. KLOTHO has been identified as having important roles in anti-aging, mineral metabolism, and vitamin D metabolism. A number of studies have indicated that KLOTHO mRNA and protein levels are reduced during acute or chronic kidney diseases in response to high local levels of reactive oxygen species (A7869).
Signs and Symptoms	As a uremic toxin, this compound can cause uremic syndrome. Uremic syndrome may affect any part of the body and can cause nausea, vomiting, loss of appetite, and weight loss. It can also cause changes in mental status, such as confusion, reduced awareness, agitation, psychosis, seizures, and coma. Abnormal bleeding, such as bleeding spontaneously or profusely from a very minor injury can also occur. Heart problems, such as an irregular heartbeat, inflammation in the sac that surrounds the heart (pericarditis), and increased pressure on the heart can be seen in patients with uremic syndrome. Shortness of breath from fluid buildup in the space between the lungs and the chest wall (pleural effusion) can also be present.
Carcinogen Classification	No indication of carcinogenicity to humans (not listed by IARC).
TSCA 등재 상태	TSCA listed

CAS No.

1335-39-3

분자식

C6H10O

평균 분자량

98.14 g/mol

단동위원소 질량

98.07316494 g/mol

SMILES

CCCC=CC=O

InChIKey

MBDOYVRWFFCFHM-UHFFFAOYSA-N

PubChem CID

10460

DTXSID

DTXSID7021609

XLogP

1.5

극성 표면적

17.1

수소 결합 공여자 수

수소 결합 수용자 수

회전 가능 결합 수

무거운 원자 수

형식 전하

복잡도

64.6

SpringerMaterials Properties

Dielectric constant

EPA

Hexenal (1335-39-3)

안전 및 규제

규제 정보

Chemical: Hexenal

기타 안전 정보

Evaluation - Chemicals not considered for in depth evaluation - Not commercially active in Australia

Treatment

Kidney dialysis is usually needed to relieve the symptoms of uremic syndrome until normal kidney function can be restored.

건강 영향

Chronic exposure to uremic toxins can lead to a number of conditions including renal damage, chronic kidney disease and cardiovascular disease.

노출 경로

Endogenous, Ingestion, Dermal (contact)

독성 요약

Uremic toxins such as 2-Hexenal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulate the production of reactive oxygen species. This seems to be mediated by the direct binding or inhibition by uremic toxins of the enzyme NADPH oxidase (especially NOX4 which is abundant in the kidneys and heart) (A7868). Reactive oxygen species can induce several different DNA methyltransferases (DNMTs) which are involved in the silencing of a protein known as KLOTHO. KLOTHO has been identified as having important roles in anti-aging, mineral metabolism, and vitamin D metabolism. A number of studies have indicated that KLOTHO mRNA and protein levels are reduced during acute or chronic kidney diseases in response to high local levels of reactive oxygen species (A7869).

Signs and Symptoms

As a uremic toxin, this compound can cause uremic syndrome. Uremic syndrome may affect any part of the body and can cause nausea, vomiting, loss of appetite, and weight loss. It can also cause changes in mental status, such as confusion, reduced awareness, agitation, psychosis, seizures, and coma. Abnormal bleeding, such as bleeding spontaneously or profusely from a very minor injury can also occur. Heart problems, such as an irregular heartbeat, inflammation in the sac that surrounds the heart (pericarditis), and increased pressure on the heart can be seen in patients with uremic syndrome. Shortness of breath from fluid buildup in the space between the lungs and the chest wall (pleural effusion) can also be present.

Carcinogen Classification

No indication of carcinogenicity to humans (not listed by IARC).

TSCA 등재 상태

TSCA listed