alpha-Lactose monohydrate (HCID 104938)

이름 및 식별자

우선 이름: alpha-Lactose monohydrate
IUPAC: (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol;hydrate
현지명: 알파-D-락토제 모노수화물
영어명: Alpha-D-Lactose monohydrate
분자식: C12H24O12
분자량: 360.31

이름 및 동의어

5989-81-1alpha-Lactose monohydrateDTXSID1052828alpha-D-Glucopyranose, 4-O-beta-D-galactopyranosyl-, monohydrateRefChem:1076517DTXCID90820517611-913-4Lactose monohydratealpha-D-Lactose monohydrateD-Lactose monohydrate64044-51-5Respitose

이름 더 보기

수크로스알파-D-락토제모노수화물알파-D-락토제모노수화물(ALPHA-D-LACTOSEMONOHYDRATE)α-Lactoseα-Lactose monohydrateα-D-Lactose monohydrateMILK SUGARALPHA-D-LACTOSEPharmatose 150MLACTOSE MONOHYDRATE (ALPHA-FORM)A-LACTOSE

alpha-lactose hydrateLactose monohydrate [NF](2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol;hydrateEWQ57Q8I5Xa-D-Glucopyranose, 4-O-b-D-galactopyranosyl-, monohydrateInhalac 120 (contains b anomer)d-(+)-lactose monohydrateLactose monohydrate (NF)

데이터베이스 식별자

CAS: 5989-81-1、64044-51-5、66857-12-3
PubChem CID: 104938
DTXSID: DTXSID1052828
ChEBI: CHEBI:189432
UNII: EWQ57Q8I5X
EC Number: 611-913-4

물성

구조 계산 물성

극성 표면적: 191 Å²
수소 결합 공여자 수: 9
수소 결합 수용자 수: 12
회전 가능 결합 수: 4
무거운 원자 수: 24
형식 전하: 0
복잡도: 382

실험 및 물리화학적 성질

Physical DescriptionSolid; [Merck Index]

물리화학적 성질

녹는점: 219 °C · 219 °C
끓는 점: 412.35 °C · 412.35°C (rough estimate)
밀도: 1 · 1,53 g/cm3
굴절률: 1.648 · 1.6480 (estimate)
저장 조건: Inert atmosphere,Room Temperature
용해도: 2 O: · H2O: 가용성1M, 투명, 무색
물리적 상태: Solid
색상: 흰색에서 황백색까지
수소이온지수(pH): pH (50g/l, 25℃) : 4.0～6.0
생물학적 소스: bovine milk
수용성: 물에 용해됩니다.
안정성: 흡습성
InChI: 1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1
InChIKey: WSVLPVUVIUVCRA-KPKNDVKVSA-N
SMILES: [H]O[H].OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
EPA: 4 · .alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, hydrate (1:1) (5989-81-1)

화학적 성질

White powder

안전 및 규제

GHS 분류

GHS Classification · 3건

This chemical does not meet GHS hazard criteria for 100% (63 of 63) of all reports.

Not Classified；Reported as not meeting GHS hazard criteria by 63 of 63 companies. For more detailed information, please visit ECHA C&L website.

Aggregated GHS information provided per 63 reports by companies from 2 notifications to the ECHA C&L Inventory.；Reported as not meeting GHS hazard criteria per 63 of 63 reports by companies.；There are 0 notifications provided by 0 of 63 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 4건

Chemical: .alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, monohydrate

Chemical: D-Glucose, 4-O-.beta.-D-galactopyranosyl-, monohydrate

Lactose monohydrate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety Information · 2건

IMAP assessments - D-Glucose, 4-O-.beta.-D-galactopyranosyl-, monohydrate: Human health tier I assessment

IMAP assessments - .alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, monohydrate: Human health tier I assessment；Evaluation - Chemicals that are unlikely to require further regulation to manage risks to environment

Hazards SummaryThe standard milk sugar and lactose of pharmacy; [Merck Index] May cause irritation; [Sigma-Aldrich MSDS] See Lactose.

Hazard Classes and CategoriesNot Classified

규제 정보

Regulatory Information · 4건

Chemical: .alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-, monohydrate

Chemical: D-Glucose, 4-O-.beta.-D-galactopyranosyl-, monohydrate

Lactose monohydrate: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk: 3
tsca: Yes
HS 번호: 17021100
risk_code: 40-36/37/38
hazard_code: Xi
safety_code: 24/25-36-26
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

용도 및 제조

Uses · 1건

Found in the milk of mammals; Used as a nutrient, in baking mixtures, as pharmaceutic aid (tablet and capsule excipient and diluent), for lactic acid fermentation in ensilage and foods, in culture media, and as chromatographic adsorbent in analytical chemistry; [Merck Index]

Household ProductsInformation on 2 consumer products that contain alpha-Lactose monohydrate in the following categories is provided:；• Personal Care

응용 분야

용도alpha-D-Lactose monohydrate is used as a carrier and stabiliser of aromas, pharmaceutical products, Food industry.

제조 방법 · 1건

생산 방법A suspension of a-lactose monohydrate crystals in a lactose solution is atomized and dried in a spray drier. Approximately 10–20% of the total amount of lactose is in solution and the remaining 80–90% is present in the crystalline form. The spray-drying process predominantly produces spherical particles. The compactibility of the material and its flow characteristics are a function of the primary particle size of the lactose monohydrate and the amount of amorphous lactose.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

山西锦洋药用辅料有限公司18234787927

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

上海惠诚生物科技有限公司60498804 18930850192 · [email protected]

上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]

추가 설명 · 1건

정의A sugar that occurs in many plants. It is extracted commercially from sugar cane and sugar beet. Sucrose is a disaccharide formed from a glucose unit and a fructose unit. It is hydrolyzed to a mixture of fructose and glucose by the enzyme invertase. Since this mixture has a different optical rotation (levorotatory) than the original sucrose, the mixture is called invert sugar.

연결된 노트

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알파-D-락토제 모노수화물

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