기본 정보
- CAS
25535-16-4- 표준 SMILES
CC[N+](C)(CC)CCC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc21.[I-].[I-]- InChIKey
XJMOSONTPMZWPB-UHFFFAOYSA-M- 분자식
- C27H34I2N4
- 평균 분자량
- 668.4 g/mol
- 단동위원소 질량
- 668.08729
이름 및 식별자
- 우선 이름
- Propidium Iodide
- IUPAC
- 3-(3,8-diamino-6-phenylphenanthridin-5-ium-5-yl)propyl-diethyl-methylazanium diiodide
- 현지명
- 요오드화프로피듐
- 영어명
- Propidium iodide
- 분자식
- C27H34IN4+
- 분자량
- 541.5
이름 및 동의어
이름 더 보기
데이터베이스 식별자
- CAS
25535-16-4- PubChem CID
- 104981
- DTXSID
DTXSID20894084- ChEBI
CHEBI:51240- UNII
- TP416O228T
- EC Number
- 247-081-0
물성
구조 계산 물성
- 극성 표면적
- 55.9 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 4
- 회전 가능 결합 수
- 7
- 무거운 원자 수
- 33
- 형식 전하
- 0
- 복잡도
- 555
실험 및 물리화학적 성질
물리화학적 성질
- 녹는점
- 220 · 220-225 °C (dec.) (lit.)
- 밀도
- 1.5072 · 1.5072 (estimate)
- 저장 조건
- 2 · 2-8°C
- 용해도
- 혼합하기가 어렵습니다.
- 물리적 상태
- 색다른 가루
- 색상
- 진한 빨간색
- 수용성
- 1 mg/ml로 · 1mg/ml로 물에 용해됨
- BRN
- 3843838 · 3843838
- 주요 응용
- 세포사멸 감지;세포주기 분석
- InChIKey
- ISKCJFFZOPXOFC-UHFFFAOYSA-N
- SMILES
- C([N+]1=C2C=C(N)C=CC2=C2C=CC(N)=CC2=C1C1C=CC=CC=1)CC[N+](C)(CC)CC.[I-]
화학적 성질
Propidium iodide is a dark red to reddish-brown liquid that is soluble in a variety of organic solvents. It is light-sensitive and may decompose upon prolonged exposure to light, leading to the formation of iodine. For optimal stability, it should be stored in a cool, dark place under an inert atmosphere.
안전 및 규제
GHS 분류
GHS Classification
Warning
H315 (98.8%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (98.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (98.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H341 (26.1%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]
P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 165 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
유해성 정보
규제 정보
안전 데이터
- wgk
- 3
- rtecs
- SF7949600
- HS 번호
- 29339900
- risk_code
- 36/37/38-68-67-48/20/22-40-36/38-22-20-63
- hazard_code
- Xi,Xn
- safety_code
- 26-36-22-36/37
- F 고인화성물질
- 3-8-10-23
- 스토리지 클래스
- 12 - Non Combustible Liquids
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA.
Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.
용도 및 제조
Uses
Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits. [ChemIDplus]
응용 분야
용도Propidium Iodide is a phenanthridine compound, a class of compounds with reported activity against several species of trypanosomes. Propidium iodide may be used in flow cytometry to evaluate cell viab ility when used with other dyes that stain viable cells or cells that are early in the apoptosis process.
일반 설명Extinction coefficient(493 nm): 5900 M -1cm-1;(287 nm): 55,700 M -1cm-1;
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