요오드화프로피듐

Propidium Iodide

HCID 104981

기본 정보

CAS
25535-16-4
표준 SMILES
CC[N+](C)(CC)CCC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc21.[I-].[I-]
InChIKey
XJMOSONTPMZWPB-UHFFFAOYSA-M
분자식
C27H34I2N4
평균 분자량
668.4 g/mol
단동위원소 질량
668.08729

이름 및 식별자

우선 이름
Propidium Iodide
IUPAC
3-(3,8-diamino-6-phenylphenanthridin-5-ium-5-yl)propyl-diethyl-methylazanium diiodide
현지명
요오드화프로피듐
영어명
Propidium iodide
분자식
C27H34IN4+
분자량
541.5

이름 및 동의어

propidium iodide25535-16-4Propidium diiodideCHEBI:51240TP416O228T3,8-Diamino-5-(3-(diethylmethylammonio)propyl)-6-phenylphenanthridinium diiodideDTXSID208940843,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodidePhenanthridinium, 3,8-diamino-5-(3-(diethylmethylammonio)propyl)-6-phenyl-, diiodideNSC-169541Diiodide, PropidiumIodide, Propidium
이름 더 보기
요오드화프로피듐Propidium iodide solution3,8-DIAMINO-5-(3-DIETHYLAMINOPROPYL)-6-PHENYLPHENANTHRIDINIUM IODIDE METHIODIDEPI (Red)Nsc169541C27H34IN4PI solution-Cellstain-PiPI(Powder form)
RefChem:176408DTXCID101324125247-081-0Propidiumiodide3,8-Diamino-5-(3-(diethyl(methyl)ammonio)propyl)-6-phenylphenanthridin-5-ium iodidePropidium (Iodide)MFCD000119213-(3,8-diamino-6-phenylphenanthridin-5-ium-5-yl)propyl-diethyl-methylazanium diiodide

데이터베이스 식별자

CAS
25535-16-4
PubChem CID
104981
DTXSID
DTXSID20894084
ChEBI
CHEBI:51240
UNII
TP416O228T
EC Number
247-081-0

물성

구조 계산 물성

극성 표면적
55.9 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
4
회전 가능 결합 수
7
무거운 원자 수
33

실험 및 물리화학적 성질

Physical DescriptionDark red solid; [Sigma-Aldrich MSDS]

물리화학적 성질

녹는점
220 · 220-225 °C (dec.) (lit.)
밀도
1.5072 · 1.5072 (estimate)
저장 조건
2 · 2-8°C
용해도
혼합하기가 어렵습니다.
물리적 상태
색다른 가루
색상
진한 빨간색
화학적 성질 · 1건

Propidium iodide is a dark red to reddish-brown liquid that is soluble in a variety of organic solvents. It is light-sensitive and may decompose upon prolonged exposure to light, leading to the formation of iodine. For optimal stability, it should be stored in a cool, dark place under an inert atmosphere.

안전 및 규제

GHS 분류

GHS Classification · 5건

Warning

H315 (98.8%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (98.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (98.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H341 (26.1%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]

P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 165 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory InformationPhenanthridinium, 3,8-diamino-5-3-(diethylmethylammonio)propyl-6-phenyl-, diiodide: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummarySubcutaneous LD50 (mouse) = 16 mg/kg; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS] See Homidium bromide. See Iodine for the TLV of Iodides.
Hazard Classes and CategoriesSkin Irrit. 2 (98.8%);Eye Irrit. 2 (98.8%);STOT SE 3 (98.8%);Muta. 2 (26.1%)

규제 정보

Regulatory InformationPhenanthridinium, 3,8-diamino-5-3-(diethylmethylammonio)propyl-6-phenyl-, diiodide: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk
3
rtecs
SF7949600
HS 번호
29339900
risk_code
36/37/38-68-67-48/20/22-40-36/38-22-20-63
hazard_code
Xi,Xn
safety_code
26-36-22-36/37

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 3건

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA.

Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.

용도 및 제조

Uses · 1건

Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits. [ChemIDplus]

응용 분야 · 2건

용도Propidium Iodide is a phenanthridine compound, a class of compounds with reported activity against several species of trypanosomes. Propidium iodide may be used in flow cytometry to evaluate cell viab ility when used with other dyes that stain viable cells or cells that are early in the apoptosis process.

일반 설명Extinction coefficient(493 nm): 5900 M -1cm-1;(287 nm): 55,700 M -1cm-1;

공급사100 곳

北京华美互利生物化工010-56205725 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]

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