루미놀

Luminol

HCID 10638

기본 정보

CAS
521-31-3
표준 SMILES
Nc1cccc2c(=O)[nH][nH]c(=O)c12
InChIKey
HWYHZTIRURJOHG-UHFFFAOYSA-N
분자식
C8H7N3O2
평균 분자량
177.16 g/mol
단동위원소 질량
177.05382646

개요

O-aminophthalyl hydrazide appears as yellow crystals or light beige powder. (NTP, 1992)

이름 및 식별자

우선 이름
Luminol
IUPAC
5-amino-2,3-dihydrophthalazine-1,4-dione
현지명
루미놀
영어명
Luminol
분자식
C8H7N3O2
분자량
177.16

이름 및 동의어

LUMINOL521-31-35-Amino-2,3-dihydro-1,4-phthalazinedione3-Aminophthalic hydrazide1,4-Phthalazinedione, 5-amino-2,3-dihydro-o-aminophthalylhydrazide3-Aminophthalic acid hydrazideDTXSID5024504o-Aminophthaloyl hydrazide5EXP385Q4FNSC-5064DTXCID004504
이름 더 보기
루미놀5-aminophthalazine-1,4-diol3-Aminophthalhydrazide (Luminol)Luminol and sodium saltuminoLRuminosLuMinol 97%
RefChem:5965208-309-43-Aminophthalhydrazide5-amino-2,3-dihydrophthalazine-1,4-dione5-Amino-1,2,3,4-tetrahydrophthalazine-1,4-dioneMFCD000068903-AminophthalylhydrazideNSC 5064

데이터베이스 식별자

CAS
521-31-3
PubChem CID
10638
DTXSID
DTXSID5024504
ChEMBL
CHEMBL442329
UNII
5EXP385Q4F
EC Number
208-309-4
Nikkaji
J9.432C

물성

구조 계산 물성

XLogP
0.3
극성 표면적
84.2 Ų
수소 결합 공여자 수
3
수소 결합 수용자 수
3
회전 가능 결합 수
0
무거운 원자 수
13

실험 및 물리화학적 성질

Chemical ClassesDyes -> Indicator Dyes
SpringerMaterials PropertiesLuminescence
Solubilityless than 1 mg/mL at 66 °F (NTP, 1992)
Melting Point606 to 608 °F (NTP, 1992)
Physical Description · 2건

O-aminophthalyl hydrazide appears as yellow crystals or light beige powder. (NTP, 1992)

Yellow or light beige solid; [CAMEO] Light yellow powder; [Sigma-Aldrich MSDS]

물리화학적 성질

녹는점
300 °C · >300 °C (lit.)
끓는 점
309.07 °C · 309.07°C (rough estimate)
밀도
1.3393 · 1.3393 (rough estimate)
굴절률
1.65 · 1.6500 (estimate)
저장 조건
30 °C · Store below +30°C.
용해도
물에 불용성, 디메틸설폭사이드에 용해됨.

화학적 성질

yellow crystals or beige powder

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 1.7% (1 of 59) of reports.

Warning

H302 (15.3%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 59 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

Chemical: 1,4-Phthalazinedione, 5-amino-2,3-dihydro-

5-Amino-2,3-dihydro-1,4-phthalazinedione: Does not have an individual approval but may be used under an appropriate group standard

Fire HazardsFlash point data for this material are not available, but it is probably combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes. (NTP, 1992)
Hazards SummaryAcute oral lethal-dose > 500 mg/kg; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS]
Reactive GroupAmides and Imides
Reactivity ProfileOxidation of O-AMINOPHTHALYL HYDRAZIDE is accompanied by a striking emission of light. (NTP, 1992). It is incompatible with strong oxidizing agents, strong reducing agents, strong acids, and strong bases [Sigma-Aldrich MSDS].

안전 및 보호

Fire FightingFires involving this material can be controlled with a foam, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then dampen the solid spill material with toluene, then transfer the dampened material to a suitable container. Use absorbent paper dampened with toluene to pick up any remaining material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent-wash all contaminated surfaces with toluene followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
TH8890060
HS 번호
29339990
risk_code
36/37/38-22-20/21/22
hazard_code
Xi,Xn

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 2건

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

Compound such as LUMINESCENT PROTEINS that cause or emit light (PHYSICAL LUMINESCENCE).

용도 및 제조

UsesUsed to detect copper, iron, peroxides, and cyanides--produces light when oxidized; [Merck Index]
General Manufacturing Information1,4-Phthalazinedione, 5-amino-2,3-dihydro-: ACTIVE
응용 분야 · 2건

용도Luminol is used in the detection of copper, iron, peroxides and cyanides. It exhibits chemiluminescence and utilized to measure opsonic and phagocytic function. It acts as a biological sensor and involved in the detection of polymorphonuclear leukocytes response in a patient with a myeloperoxidase deficiency. Further, it is used as a forensic test for blood.

일반 설명Yellow crystals or light beige powder.

공급사100 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
重庆渝恩素能科技有限公司13883023934; 13883023934
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

관련 반응

5건

화합물 노트

불러오는 중…