기본 정보
- CAS
521-31-3- 표준 SMILES
Nc1cccc2c(=O)[nH][nH]c(=O)c12- InChIKey
HWYHZTIRURJOHG-UHFFFAOYSA-N- 분자식
- C8H7N3O2
- 평균 분자량
- 177.16 g/mol
- 단동위원소 질량
- 177.05382646
개요
O-aminophthalyl hydrazide appears as yellow crystals or light beige powder. (NTP, 1992)
이름 및 식별자
- 우선 이름
- Luminol
- IUPAC
- 5-amino-2,3-dihydrophthalazine-1,4-dione
- 현지명
- 루미놀
- 영어명
- Luminol
- 분자식
- C8H7N3O2
- 분자량
- 177.16
이름 및 동의어
이름 더 보기
데이터베이스 식별자
- CAS
521-31-3- PubChem CID
- 10638
- DTXSID
DTXSID5024504- ChEMBL
CHEMBL442329- UNII
- 5EXP385Q4F
- EC Number
- 208-309-4
- Nikkaji
- J9.432C
물성
구조 계산 물성
- XLogP
- 0.3
- 극성 표면적
- 84.2 Ų
- 수소 결합 공여자 수
- 3
- 수소 결합 수용자 수
- 3
- 회전 가능 결합 수
- 0
- 무거운 원자 수
- 13
- 형식 전하
- 0
- 복잡도
- 254
실험 및 물리화학적 성질
Physical Description
O-aminophthalyl hydrazide appears as yellow crystals or light beige powder. (NTP, 1992)
Yellow or light beige solid; [CAMEO] Light yellow powder; [Sigma-Aldrich MSDS]
물리화학적 성질
- 녹는점
- 300 °C · >300 °C (lit.)
- 끓는 점
- 309.07 °C · 309.07°C (rough estimate)
- 밀도
- 1.3393 · 1.3393 (rough estimate)
- 굴절률
- 1.65 · 1.6500 (estimate)
- 저장 조건
- 30 °C · Store below +30°C.
- 용해도
- 물에 불용성, 디메틸설폭사이드에 용해됨.
- 산도 계수 (pKa)
- 10.5 · (Calcd.) 10.50 ± 0.20;;0.58 ± 0.20(at 25℃)
- 물리적 상태
- 가루
- 색상
- 진한 녹색에서 진한 파란색-보라색
- 수용성
- 19 · 19ºC에서 <0.1g/100mL
- Merck
- 14 · 14,5600
- BRN
- 383929 · 383929
- 안정성
- 안정적인. 타기 쉬운. 강산화제, 강산, 강염기, 강환원제와 호환되지 않습니다. 산화제와 반응하면 빛을 방출합니다.
- 주요 응용
- 야간 투시 장치, 제품 위조 식별, 식품 중 질화물 측정, 분석 화학, 의약품, 생체 물질 중 요오드 측정, 식세포 평가, 종양 검출, DNA, 바이오센서, 곰팡이, 박테리아, 효모 분석, 리파아제 활성 분석
- InChI
- 1S/C8H7N3O2/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12/h1-3H,9H2,(H,10,12)(H,11,13)
- InChIKey
- HWYHZTIRURJOHG-UHFFFAOYSA-N
- SMILES
- Nc1cccc2C(=O)NNC(=O)c12
- LogP
- -0.245 · -0.245 (est)
- NIST
- 3 · 3-Aminophthalhydrazide(521-31-3)
- EPA
- Luminol (521-31-3)
화학적 성질
yellow crystals or beige powder
안전 및 규제
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 1.7% (1 of 59) of reports.
Warning
H302 (15.3%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 59 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Regulatory Information
Chemical: 1,4-Phthalazinedione, 5-amino-2,3-dihydro-
5-Amino-2,3-dihydro-1,4-phthalazinedione: Does not have an individual approval but may be used under an appropriate group standard
안전 및 보호
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Nonfire Spill Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then dampen the solid spill material with toluene, then transfer the dampened material to a suitable container. Use absorbent paper dampened with toluene to pick up any remaining material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent-wash all contaminated surfaces with toluene followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Personal Protective Equipment (PPE)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
안전 데이터
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- TH8890060
- HS 번호
- 29339990
- risk_code
- 36/37/38-22-20/21/22
- hazard_code
- Xi,Xn
- safety_code
- 26-36/37-37/39-36
- F 고인화성물질
- 10-23
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Compound such as LUMINESCENT PROTEINS that cause or emit light (PHYSICAL LUMINESCENCE).
용도 및 제조
응용 분야
용도Luminol is used in the detection of copper, iron, peroxides and cyanides. It exhibits chemiluminescence and utilized to measure opsonic and phagocytic function. It acts as a biological sensor and involved in the detection of polymorphonuclear leukocytes response in a patient with a myeloperoxidase deficiency. Further, it is used as a forensic test for blood.
일반 설명Yellow crystals or light beige powder.
상·하류 제품 정보
상류 원료
공급사100 곳
관련 반응
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