| GHS 분류 | DangerH225 (89.5%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 1875 reports by companies from 22 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.H225: Highly Flammable liquid and vapor [Danger Flammable liquids] |
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| 규제 정보 | Chemical: Methane, thiobis-Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)Methane, 1,1'-thiobis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Methane, 1,1'-thiobis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Reg. (EU) 2021/1451Status: Active Update: 13-12-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/13649Methane, thiobis-: HSNO Approval: HSR001135 Approved with controls |
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| 운송 라벨(DOT) | Flammable Liquid |
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| 화재 위험 | Special Hazards of Combustion Products: Toxic and irritating sulfur dioxide is formed.· HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire. Vapour/air mixtures are explosive. |
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| 화재 가능성 | Highly flammable |
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| 건강 유해성 | Inhalation causes moderate irritation of upper respiratory system. Contact of liquid with eyes causes moderate irritation. Repeated contact with skin may extract oils and result in irritation. Ingestion causes nausea and irritation of mouth and stomach. (USCG, 1999)· May cause toxic effects if inhaled or absorbed through skin. |
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| 유해성 요약 | Liquid can cause first degree burns after short contact. [CHRIS] Decomposes on heating to release hydrogen sulfide and sulfur oxides[ICSC] Low toxicity after skin or inhalation exposure[HSDB] When applied to the skin, under a patch, for 48 hours, 1% dimethyl sulfide in petroleum jelly does not cause skin irritation. Dimethyl sulfide vapor can reach high concentrations at room temperature and act as a simple asphyxiant. It is a skin and respiratory tract irritant and can cause CNS depression after heavy inhalation exposure. From a case report, one worker in a storage tank died after exposure to about 500,000 ppm. The death was attributed to dimethyl sulfide toxicity and simple asphyxiation. [CHEMINFO] |
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| 운송 번호 및 가이드(DOT) | 1164 130 |
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| 반응성 그룹 | Sulfides, Organic |
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| UN 분류 | UN Hazard Class: 3UN Pack Group: II |
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| Special Reports | European Commission, ESISIUCLID Dataset, Dimethyl sulphide (75-18-3) p.22 (2000 CD-ROM edition) contains information on use, toxicology, and environmental effects of this chemical as supplied to the European Union by industry.[Available from the Database Query page, as of August 24, 2009. http://esis.jrc.ec.europa.eu/] |
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| Reactivity Alerts | Highly Flammable |
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| Reactivity Profile | Organosulfides, such as DIMETHYL SULFIDE, are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Dimethyl sulfide rapidly decomposes dibenzoyl peroxide explosively in the absence of solvent, [J. Org. Chem., 1972, 37, 2885]. The sulfide also decomposes xenon difluoride explosively at ambient temps, [J, Chem Soc., 1984, 2827]. Interaction of dimethyl sulfide and oxygen is explosive at 210 °C and above, [Atmos. Environ., 1967, 1, 491-497]. A delayed explosion occurred in a system containing nitric acid, dimethyl sulfide, and 1, 4-dioxane, even with cooling with liquid nitrogen, [Chem. Abs., 1972, 76, 13515]. |
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| 소화 | Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious)]:Use powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water. |
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| 응급 조치 | Fresh air, rest. Refer for medical attention.Remove contaminated clothes. Rinse and then wash skin with water and soap.First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give one or two glasses of water to drink. Refer for medical attention . |
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| 누출 비상 조치 | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. |
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| 응급 처치 | INHALATION: move victim to fresh air at onceenforce rest, and keep warmget medical attention immediately.General First Aid: |
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| 안전 보관 | Fireproof. Separated from strong oxidants. Cool. |
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| Firefighting Hazards | Auto flammability: 205 °C at 1013 hPa |
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| 노출 관리 및 개인 보호 | · Wear positive pressure self-contained breathing apparatus (SCBA). |
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| 소화 절차 | Use CO2, dry chemical.This chemical is a combustible liquid. Poisonous gases including hydrogen sulfide and sulfur oxides are produced in fire. Use dry chemical, carbon dioxide, water spray, fog, or foam extinguishers. Wear self-contained breathing apparatus and full protective clothing. If it can be done safely, move container from fire area. For massive fire in cargo area, use unmanned hose holder or monitor nozzlesif this is impossible, withdraw from area and let fire burn. Isolate for 1/2 mile in all directions if tank car of truck is involved in fire. Vapors are heavier than air and will collect in low areas. Vapors may travel long distances to ignition sources and flashback. Vapors in confined areas may explode when exposed to fire. Containers may explode in fire. Storage containers and parts of containers may rocket great distances, in many directions. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Notify local health and fire officials and pollution control agencies. From a secure, explosion-proof location, use water spray to cool exposed containers. If cooling streams are ineffective (venting sound increases in volume and pitch, tank discolors or shows any signs of deforming), withdraw immediately to a secure position.Water may be ineffective. |
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| 보관 조건 | Before entering confined space where this chemical may be present, check to make sure that an explosive concentration does not exist. Store in tightly closed containers in a cool, well ventilated area. Metal containers involving the transfer of this chemical should be grounded and bonded. Where possible, automatically pump liquid from drums or other storage containers to process containers. Drums must be equipped with self-closing valves, pressure vacuum bungs, and flame arresters. Use only non-sparking tools and equipment, especially when opening and closing containers of this chemical. Sources of ignition, such as smoking and open flames, are prohibited where this chemical is used, handled, or stored in a manner that could create a potential fire or explosion hazard. Wherever this chemical is used, handled, manufactured, or stored, use explosion-proof electrical equipment and fittings. |
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| 정리 방법 | SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.Evacuate and restrict persons not wearing protective equipment from area of spill or leak until cleanup is complete. Remove all ignition sources. Establish forced ventilation to keep levels below explosive limit. Absorb liquids in vermiculite, dry sand, earth, peat, carbon, or a similar material, and deposit it in sealed containers. Keep this chemical out of a confined space, such as a sewer, because of the possibility of an explosion, unless the sewer is designed to prevent the build-up of explosive concentrations. It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters.Waste gases from sewage treatment (720 cu m/min) were scrubbed with a soln containing 9x10-3 mol NaClO/L. Dimethyl sulfide content was reduced from 1.4 to 0.043 ppm.A waste gas-O3 mixture from sewage treatment containing Dimethyl sulfide at 10 ppm was passed through a bed of NaClO-impregnated activated carbon to give a 96% removal rate.Cells of Thiobacillus thioparus TK-m were immobilized on cylindrical porous polypropylene pellets (5mm x 5 mm, apparent density 0.3, water retention 215 g/l) which were packed in an acrylic cylinder of 50 mm inner diameter up to the ht of 800 mm. When a sulfur-containing malodorous gas was charged to this packed tower at the superficial velocity of 0.1 m/sec, max loading capacity for a malodorous gas to attain the removal rate of 95% or more was 3.65 mM/l/day for dimethyl sulfide. At this time the inlet concn of the malodorous compound was 7.44 ul/l for dimethyl sulfide. Higher loading resulted in greater removal quantities, and the removal rate was not overly affected by the presence of a large amount of easily decomposable hydrogen sulfide. |
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| 비화재 누출 대응 | Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious)]: |
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| 처리 방법 | SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air qualitypotential migration in soil or watereffects on animal and plant lifeand conformance with environmental and public health regulations.AEROBIC: Dimethyl sulfide was initially present in a wastewater/recycled sludge mixture at 150 (ug/kg)/(ug/L)following activated sludge treatment, effluent concns were below the detection limit(7). Radiolabeled-dimethyl sulfide added to the head space over 1 ml of freshwater lake sediment was metabolized to methane and carbon dioxide33 and 5% radiolabeled carbon was converted to methane and carbon dioxide, respectively, in 8 hours(2). No degradation of dimethyl sulfide occurred in sterilized (heat killed - 70 °C, 1 hr) samples of sediment(2). Addition of dimethyl sulfide to various anoxic aquatic sediments (e.g. fresh water, estuarine, alkaline/hypersaline) stimulated methane production(3). The yield of methane from dimethyl sulfide typically ranged between 52-63%, although high concns of dimethyl sulfide inhibited methanogenesis in sediment from alkaline lakes(3). Metabolism resulted in appearance of methanethiol as a transient intermediate(3). Dimethyl sulfide was completely biodegraded in anoxic salt marsh sediments within 11 days with the production of methanethiol and methane(4). Biological consumption rates of dimethyl sulfide, in seawater samples collected in the eastern Pacific Ocean, ranged from 1.1 nM/day to 18.0 nM/day, giving turnover times of 0.6 to 4.6 days(5). The conversion efficiency from added dimethyl sulfide to methane of an algal mat and sediments obtained from a hypersaline pond was 11.2%(6).AEROBIC: Dimethyl sulfide, present at 2.5 mg/L, showed 100% degradation in 2 days using a freshwater sediment inoculum(1). Dimethyl sulfide, present at 0.43 g/L, showed 100% degradation in 4 days using an acclimated, activated sewage sludge inoculum(2)dimethyl sulfide was found to be oxidized to sulfate. Therefore, dimethyl sulfide is expected to biodegrade repidly under aerobic conditions(SRC).ANAEROBIC: Dimethyl sulfide, present at 3.4 mg/L, showed 100% degradation in 8 days using a freshwater sediment inoculum under anoxic conditions(1). Dimethylsulfide, present at 0.3 mg/L, showed 100% degradation in 2 days using an anoxic salt marsh sediment as inoculum(2). Therefore, dimethyl sulfide is expected to biodegrade rapidly under anaerobic conditions(SRC).Photooxidation reduced sulfur cmpd pollution. |
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| 체내 부담 | Dimethyl sulfide was detected in expired air from 54 carefully selected healthy, nonsmokers as follows: 387 samples, 41.6% pos, mean concn 0.99 ng/l(1). It was detected in expired air from 6 out of 8 subjects at a range of measured expiration rates of 0.54-53.0 ug/hr(2). The concentration in breath samples collected from 14 persons exposed to organic reduced sulfur compounds in sulfate pulp mills ranged from 0.04 to 0.69 cu cm/cu m(3). |
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| 상호 작용 | Tolerance against the rat lung edema response to ozone inhalation was not incr by intraperitoneal injection of dimethyl sulfide.Dimethyl sulfoxide suppresses conversion of the prodrug sulindac to its bioactive sulfide metabolite (SD). During continuous iv infusions of sulindac (1 mg/kg/hr), plasma concn of SD at steady-state equilibrium were 80% lower when DMSO was infused concomitantly at 0.34 ml/kg/hrwhereas sulindac plasma concn were not significantly affected by DMSO. DMSO was only a weak inhibitor of SD oxidation in vitro and did not affect the rate of SD elimination in vitro. In contrast, dimethyl sulfide a metabolite of DMSO, was a potent inhibitor of SD oxidase in vitro.Adult male rats were injected with sodium arsenite (4 mg/kg, sc) 10 min prior to injection of dimethyl sulfide. Neither compound caused mortality when given alone (n = 4). Dimethyl sulfide (320 mg S/kg, sc) resulted in no toxic signs or mortality with or without arsenite (n = 4). |
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| 생태독성 수치 | LC50Species: Daphnia pulex (Crustacea)Concentration: 150 mg/L for 24 hr (20 °C) /Conditions of bioassay not specified in source examined/EC50Species: Daphnia magna (Water flea)Concentration: 14300 ug/L for 24 hrEffect: intoxication, immobilization /Conditions of bioassay not specified in source examined/ |
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| 환경 거동 | TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 6.3(SRC), determined from a water solubility of 22,000 mg/L(2) and a regression-derived equation(3), indicates that dimethyl sulfide is expected to have very high mobility in soil(SRC). Volatilization of dimethyl sulfide from moist soil surfaces is expected to be an important fate process(SRC) given a measured Henry's Law constant of 1.61X10-3 atm-cu m/mole(4). Dimethyl sulfide is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 502 mm Hg at 25 °C(5). 100% degradation over 2 days in an aerobic test using a freshwater sediment inoculum(6) suggests that biodegradation is an important environmental fate process in soil(SRC).AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 6.3(SRC), determined from a water solubility of 22,000 mg/L(2) and a regression-derived equation(3), indicates that dimethyl sulfide is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(4) based upon a measured Henry's Law constant of 1.61X10-3 atm-cu m/mole(5). Using this Henry's Law constant and an estimation method(4), volatilization half-lives for a model river and model lake are 3 hours and 3 days, respectively(SRC). According to a classification scheme(6), an estimated BCF of 3.2(SRC), from a water solubility of 22,000 mg/L(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). 100% degradation over 2 days in an aerobic test using a freshwater sediment inoculum(8) suggests that biodegradation is an important environmental fate process in water(SRC).ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), dimethyl sulfide, which has a vapor pressure of 502 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase dimethyl sulfide is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(3)the half-life for this reaction in air is estimated to be about 3 days(SRC), calculated from its rate constant of 4.82X10-12 cu cm/molecule-sec at 25 °C(3). Dimethyl sulfide does not absorb light at wavelengths >290 nm(4) and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).Role of organic sulfides in the atmosphere and emission rate of biogenic organic sulfides relative to that of hydrogen sulfide is not well understood. Absolute values of rate constants were detn for the reaction of ground-state oxygen atoms, O(3P), with dimethyl sulfide by using a phase shift technique in which O atoms were generated by Hg-sensitized decomposition of nitrous oxide and monitored by the chemiluminescence from their reaction with nitric oxide. Between 298 and K, the rate constants were represented by the following equation: k= (2.28 +/- 0.11)-12 exp((-2075 +/- 268)/T). |
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| 식품 조사 수치 | Dimethyl disulfide has been detected in the volatile components of Beaufort cheese(1), of strawberries(2), of mutton, chicken, beef and pork(3), and of cooked mussels(4). Dimethyl disulfide has been detected in samples of various dried legumes at the following concentrations: lima beans, 8.6-176.7 ppbpinto beans, 17.3-25.3 ppbred kidney beans, 26.9 ppbblack beans, 15.2 ppbnavy beans, 401.7 ppbmung beans, 47.7 ppbsoybeans, 48.5 ppbsplit peas, 8.0 ppband lentils, 10.5-53.6 ppb(5). Dimethyl sulfide has been detected in the volatiles from popped popcorn at a concentration of 70 ug/kg dry weight(6). Dimethyl sulfide has been detected in the volatiles from stir-fried garlic at a concentration of 19.6% of the total analytes(7). |
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| 유해 작용 | Neurotoxin - Other CNS neurotoxin |
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| 노출 경로 | The substance can be absorbed into the body by inhalation of its vapour and by ingestion. |
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| Milk Concentrations | ENVIRONMENTAL: Dimethyl sulfide has been detected in feed-flavored milk(1). |
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| 생태독성 발췌 | /FIELD STUDIES/ This study of the origin and fate of dimethyl sulphide (DMS) in a particular and complex lagoon ecosystem such as that of the Venice lagoon focuses on the temporal evolutions of DMS concentrations in surface water together with those of dimethylsulphoniopropionate (DMSP), carbon disulphide (CS2), nutrients (nitrate, nitrite, ammonium, phosphate, silicate), sulphate, chlorophyll a, chlorinity, water temperature and phytoplankton (composition and density). Measurements were made from 3 March 1997 to 23 July 1998 at three stations in the central part of the Venice lagoon. The temporal trends of DMS concentration showed an absolute maximum concentration in winter (65 nmol S/l, 19/2/1998, Stn. 1119 nmol S/l, 19/2/1998, Stn. 229 nmol S/l, 17/2/1998, Stn. 3) and two relative maxima in the spring-summer period. The spring-summer secondary maxima of DMS concentration were related to the maxima of DMSP and chlorophyll a concentrations and consequently to phytoplanktonic abundance while the winter DMS maximum showed no relation to DMSP or to chlorophyll a suggesting that the production and the fate of DMS could be different for the two periods. According to previous studies the CS2 concentration increased in the spring, achieved its maximum in summer, decreased in autumn and fell to its minimum in winter. |
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| Plant Concentrations | Dimethyl sulfide was the primary sulfur species determined in emissions from oat, corn, soybean, orchard grass, purple clover, and alfalfa fields, with the total sulfur emission rate ranging from 0.007 to 0.273 g sulfur/sq m/yr(1). Dimethyl sulfide has been identified in volatile emissions from evergreen cypress trees(2).There are a number of plants containing dimethyl sulfide as a natural ingredient: Brassica OleraceaAllium CepaAllium SativumAllium SchoenoprasumCamellia SinensisMentha SpicataPelargonium GraveolensSolanum Tuberosum. |
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| Signs and Symptoms | Cough. Nausea. Sore throat. Weakness.Redness. Pain. |
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| Effluent Concentrations | Dimethyl sulfide was detected in 3 out of 63 industrial wastewater effluents in the US, concn in 2 waste streams <10 ug/L, concn in 1 waste stream >100 ug/L(1). Sampling conducted in 1982 reported dimethyl sulfide as detected in the influent and effluent of a Belgian wastewater treatment plant(2). 10-50% of the total volatile sulfur compounds emitted from a pulp mill with sulphate and semi-alkaline pulping processes were identified as dimethyl sulfide(3). Air and water samples were collected at a livestock raising sitedimethyl sulfide concns ranged from 0.0004 to 0.0059 ppm in the air to 0.031 to 1.47 in the wastewater from the site(4). Head space volatile samples from stored food exudate and garden waste contained dimethyl sulfide at unreported concns(5,6). Wort boiling during beer production results in the emission of dimethyl sulfide(7).Dimethyl sulfide was detected in 3 of 4 aqueous leachate samples collected from three hazardous waste sites in Germany on unknown dates at concentrations ranging from 1000 to 24,000 ug/L, with an average of 9700 ug/L(1). Dimethyl sulfide was detected in an unknown number of air samples collected at an aerobic composting site in Belgium on an unknown date at a maximum concentration of 8.2 mg/cu m(2). Dimethyl sulfide was detected in 8 of 8 air emission samples collected at a biogas production plant in Linkoping, Sweden between November 2000 and May 2002 at concentrations ranging from 100 to 8770 ppb, with an average of 2700 ppb(3). After upgrading the pollution control processes at this biogas plant, dimethyl sulfide was detected in 3 of 6 air emission samples collected between November 2000 and May 2002 at concentrations ranging from 3 to 130 ppb, with an average of 51 ppb(3). Dimethyl sulfide was detected in an unknown number of air emission samples collected from three wastewater treatment plants in Baton Rouge, Louisiana on an unknown date at concentrations ranging from 0.007 to 51 ug/L, with a medium of 0.021 ug/L(4). Dimethyl sulfide was detected, but not quantified, in air emission samples collected from pulp mills in Finland on unknown dates(5). |
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| 대기 기준 | This action promulgates standards of performance for equipment leaks of Volatile Organic Compounds (VOC) in the Synthetic Organic Chemical Manufacturing Industry (SOCMI). The intended effect of these standards is to require all newly constructed, modified, and reconstructed SOCMI process units to use the best demonstrated system of continuous emission reduction for equipment leaks of VOC, considering costs, non air quality health and environmental impact and energy requirements. Dimethyl sulfide is produced, as an intermediate or a final product, by process units covered under this subpart. |
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| 운송 번호(UN) | UN 1164 |
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| 포장분류 | II |
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| 위험 등급 | 3 |
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