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HCID 10690생성일: 2026년 10월 26일

Gluconic Acid

https://huagongshe.com/ko/chemical/10690

Gluconic Acid 분자 구조식

식별자 및 물리적 특성

CAS No.133-42-6
분자식C6H12O7
평균 분자량196.16 g/mol
단동위원소 질량196.05830272 g/mol
SMILESO=C(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChIKeyRGHNJXZEOKUKBD-SQOUGZDYSA-N
PubChem CID10690
ChEMBLCHEMBL464345
ChEBICHEBI:33198
EC No.208-401-4
DTXSIDDTXSID8042000

화학 및 물리적 성질

XLogP-3.4
극성 표면적138
수소 결합 공여자 수6
수소 결합 수용자 수7
회전 가능 결합 수5
무거운 원자 수13
형식 전하0
복잡도170
물질 분류Other Classes -> Organic Acids
의약품Pharmaceuticals -> Listed in ZINC15
화장품Cosmetic ingredients (Gluconic Acid) -> CIR (Cosmetic Ingredient Review)HumectantSolventBuffering
LogP(분배 계수)-1.87 (estimated)
맛MILD ACID TASTE
식품 첨가물NUTRIENT SUPPLEMENT -> FDA Substance added to food
밀도1.24 @ 25 °C/4 °C1.23 g/cm³1.24 @25 °C
Color/FormNEEDLES FROM ETHANOL & ETHERCRYSTALS
용해도FREELY SOL IN WATERSLIGHTLY SOL IN ALC, INSOLUBLE IN ETHER AND MOST OTHER ORGANIC SOLVENTS316 mg/mL at 25 °CSolubility in water, g/100ml at 25 °C: 100 (good)
녹는점131 °C113 - 118 °C
Optical RotationSPECIFIC OPTICAL ROTATION: -3.49 TO +12.95 DEG @ 25 °C/D (WATER)MUTAROTATORYSADTLER REFERENCE NUMBER: 8335 (IR, PRISM)SPECIFIC OPTICAL ROTATION: -6.7 DEG @ 20 °C/D (CONCN= 1 G/100 ML WATER)
Physical DescriptionDry PowderLiquidOther SolidColourless to light yellow, clear syrupy liquidLight brown solidCommercial product is 50% aqueous solution[Hawley] 50% aqueous solution: Pale yellow liquid[MSDSonline]WHITE CRYSTALLINE POWDER.

안전 및 규제

GHS 분류This chemical does not meet GHS hazard criteria for 33% (257 of 779) of reports.WarningH315 (60.6%): Causes skin irritation [Warning Skin corrosion/irritation]P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)Aggregated GHS information provided per 779 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
규제 정보Chemical: D-Gluconic acidD-Gluconic acid is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of D-Gluconic acid are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 16-07-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/1957D-Gluconic acid: Does not have an individual approval but may be used under an appropriate group standard
기타 안전 정보IMAP assessments - D-Gluconic acid: Environment tier I assessment
화재 위험Combustible.
유해성 요약Emergency treatment: Irritants[HSDB] No significant adverse effects in chronic studies of animalsReproductive studies negativeNo data available on carcinogenicity or inhalation toxicity[OECD SIDS: Gluconic acid and its derivatives - 2004] 50% aqueous solution: A corrosive substance that can cause injury to the skin, eyes, and respiratory tractInhalation may cause chemical pneumonitis[MSDSonline]
EPA Safer ChemicalChemical: D-Gluconic acid
FIFRA 요건As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA, as amended in 1988, were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern and List D pesticides of less concern. Gluconic acid is found on List D. Case No: 4043Pesticide type: AntimicrobialCase Status: No products containing the pesticide are actively registered ... The case /is characterized/ as "cancelled." Under FIFRA, pesticide producers may voluntarily cancel their registered products. EPA also may cancel pesticide registrations if registrants fail to pay required fees or make/meet certain reregistration commitments, or if EPA reaches findings of unreasonable adverse effects.Active ingredient (AI): Gluconic acidAI Status: The active ingredient is no longer contained in any registered pesticide products ... "cancelled."Gluconic acid (and sodium salt) is exempted from the requirement of a tolerance when used as a sequestrant in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops only.
Chemical DangersOn combustion, forms carbon monoxide. Reacts with strong oxidants. The solution in water is a medium strong acid.
Hazard Classes and CategoriesSkin Irrit. 2 (60.6%)
소화Use powder, alcohol-resistant foam, water spray, carbon dioxide.
응급 조치Fresh air, rest.Rinse skin with plenty of water or shower.Rinse with plenty of water (remove contact lenses if easily possible).Rinse mouth.
안전 보관Separated from strong oxidants.
보관 조건MAY BE STORED IN STAINLESS STEEL DRUMS. /COMMERCIAL PRODUCT/
처리 방법SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
누출 처리Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.
Fire PreventionNO open flames.
Inhalation RiskEvaporation at 20 °C is negligiblea nuisance-causing concentration of airborne particles can, however, be reached quickly when dispersed.
Allowable TolerancesGluconic acid (and sodium salt) is exempted from the requirement of a tolerance when used as a sequestrant in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops only.
Ingestion PreventionDo not eat, drink, or smoke during work.
Inhalation PreventionUse local exhaust or breathing protection.
Protective Action Criteria (PAC)18 [mg/m3]200 [mg/m3]1200 [mg/m3]
유해 작용Dermatotoxin - Skin burns.
독성 요약Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org
Signs and SymptomsRedness.