532-43-4Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1.O=[N+]([O-])[O-]UIERGBJEBXXIGO-UHFFFAOYSA-N532-43-4DTXSID4038762CHEMBL2104496안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
This chemical does not meet GHS hazard criteria for 100% (67 of 67) of all reports.
Not Classified
Aggregated GHS information provided per 67 reports by companies from 2 notifications to the ECHA C&L Inventory.
Chemical: Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, nitrate (salt)
Regulation (EC) No 1831/2003 (amended)
Thiamine mononitrate: Does not have an individual approval but may be used under an appropriate group standard
개요Thiamine is a water-soluble vitamin with antioxidant, neuroprotective, and anxiolytic properties. It inhibits lipid peroxidation in rat liver microsomes and free radical oxidation of oleic acid in vitro when used at concentrations ranging from 1 to 100 μM. In vivo, thiamine (100 mg/kg) reduces hepatic levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), lipid peroxidation, and protein damage in a rat model of acute ethanol intoxication. It reverses predator stress-induced suppression of hippocampal neurogenesis and decreases the latency of step-down from a platform, indicating anxiolytic-like activity in mice. Thiamine (8.5 mg/100 g food) reduces neurodegeneration and increases survival in Slc19a3-/- mice, a model of thiamine metabolism dysfunction syndrome-2 (THMD-2).
용도Thiamine Nitrate is an orally administered vitamin. Thiamine is a essential nutrient required for carbohydrate metabolism and is involved in nerve function.
일반 설명Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Thiamine Nitrate is a mononitrate salt of thiamine. It is synthesized from thiamine hydrochloride following a sequence of steps. Thiamine Nitrate is used as a dietary supplement in crackers, eggs substitute and enriched flour.
불러오는 중…
White or almost white, crystalline powder or small, colourless crystals.
순도시험(1) 액성 : 이 품목의 수용액(1→50)의 pH는 6.5~8.0이어야 한다. (2) 염화물 : 이 품목 0.25g을 취하여 염화물시험법에 따라 시험할 때, 그 양은 0.01N 염산 0.4mL에 대응하는 양 이하이어야 한다. (3) 납 : 이 품목 5.0g을 취하여 원자흡광광도법 또는 유도결합플라즈마발광광도법에 따라 시험할 때, 그 양은 2.0ppm 이하이어야 한다.
확인시험(1)「비타민B1염산염」의 확인시험 (1), (2)에 따라 시험한다. (2) 이 품목은 확인시험법 중 질산염의 반응을 나타낸다.
정량법「비타민B1염산염」의 정량법에 따라 정량한다.